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| *A vaccine can be created to provide the specific immunity best suited for fighting the associated infection | | *A vaccine can be created to provide the specific immunity best suited for fighting the associated infection |
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− | ===Immunity to Virus Infection=== | + | ===Immunity to Viral Infection=== |
| [[Image:Virus Life Cycle.jpg|thumb|right|200px|Virus Life Cycle - Copyright Dr Brian Catchpole BVetMed PhD MRCVS]] | | [[Image:Virus Life Cycle.jpg|thumb|right|200px|Virus Life Cycle - Copyright Dr Brian Catchpole BVetMed PhD MRCVS]] |
− | *The virus life cycle consists of an extracellular phase, a replicative intracellular phase and another extracellular phase spreading viral particles to other cells to begin the life cycle again
| + | The virus life cycle consists of an extracellular phase, a replicative intracellular phase and another extracellular phase spreading viral particles to other cells to begin the life cycle again |
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− | *Immunity for the extracellular phase requires neutralising [[Immunoglobulins|'''antibody''']]
| + | Immunity for the extracellular phase requires neutralising [[Immunoglobulins|'''antibody''']]: |
− | **[[Lymphocytes#B Cells|B cells]] needed
| + | *[[Lymphocytes#B Cells|B cells]] needed |
− | **[[T cell differentiation#TH2 Cells|T helper type II cells]] needed (for the [[Major Histocompatability Complexes#MHC II|MHC class II pathway]])
| + | *[[T cell differentiation#TH2 Cells|T helper type II cells]] needed (for the [[Major Histocompatability Complexes#MHC II|MHC class II pathway]]) |
− | **Live vaccine can be used
| + | *Live, killed and subunit vaccines can be used |
− | **Killed vaccine can be used
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− | **Subunit vaccine can be used
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− | *Immunity for the intracellular phase requires [[Lymphocytes#Cytotoxic CD8+|'''CD8+ cytotoxic T cells''']]
| + | Immunity for the intracellular phase requires [[Lymphocytes#Cytotoxic CD8+|'''CD8+ cytotoxic T cells''']] and uses the [[Major Histocompatability Complexes#MHC I|MHC class I pathway]]. |
− | **[[Major Histocompatability Complexes#MHC I|MHC class I pathway]]
| + | *Only live vaccine can be used to get into cells (entering via the endogenous pathway) |
− | **Only live vaccine can be used to get into cells (entering via the endogenous pathway)
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| ===Immunity to Bacterial Infection=== | | ===Immunity to Bacterial Infection=== |