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| − | (BIV) | + | {{unfinsihed}} |
| − | *Lentivirus (non-oncogenic)
| + | |
| − | *Causes a persistent viral infection and lymphocytosis
| + | ==Description== |
| − | *Immunocompromised cattle may develop secondary infections
| + | Bovine Imunodeficiency Virus (BIV) is a Lentivirus (non-oncogenic) which causes a persistent viral infection in cattle worldwide. It was first isolated in 1969 from a cow with a wasting syndrome. |
| − | *The transmission is not well known, but the following possibilities are being researched:
| + | ==Pathogenesis== |
| − | **Through milk | + | The mechanism of transfer is not well knonw,but the following posibilites are being researched : |
| − | **Through infected semen (e.g.artificial insemination) | + | * Transplacental |
| − | **Placental transfer | + | * Transmammary |
| − | *Diagnosis: | + | * Vertical transfer through infected Semenn (e.g. Artificial inseminatio) |
| − | **Western Blot
| + | ==Clinical Signs== |
| − | **PCR | + | Bovine immunodeficiency Virus is not associated with a specific disease in cattle but has been associated with the folowing signs: |
| − | [[Category:Secondary Immunodeficiency]][[Category:Cattle]][[Category:To Do - Blood]][[Category:To Do - Clinical]] | + | * Decreased milk yield |
| | + | * clinical immunodeficiency |
| | + | * encephalitis |
| | + | * bovine paraplegic syndrome |
| | + | * skin infections |
| | + | * emaciation |
| | + | ==Diagnosis== |
| | + | *Western Blot |
| | + | *PCR |
| | + | ==Treatment and Control== |
| | + | The Incidence of Bovine immunodeficiency virus appears to be low (1%) although can reach >15 % in some herds |
| | + | ==References== |
| | + | * Merck & Co (2008) '''The Merck Veterinary Manual (Eighth Edition)''' ''Merial'' |
| | + | * Quinn, P.J., Markey, B.K., Carter, M.E., Donnelly, W.J., Leonard, F.C. (2007) '''Veterinary Microbiology and Microbial Disease''' ''Blackwell Publishing'' |
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| | + | [[Category:Secondary Immunodeficiency]][[Category:Cattle]][[Category:To Do - Blood]][[Category:To Do - Katie]] |