Changes

===Inflammation===

===Inflammation===

In addition the complement fragments released after complement (C2a C3a, C4a and especially C5a) are chemotactic for phagocytes. The smaller peptides (C3a and C5a) are also very efficient at inducing inflammation. Not only do they attract granulocytes to the site of complement activation but also stimulation their degranulation. Finally, the later components (C5 – C9) can kill pathogens directly by causing cell lysis. In clinical terms, this is effective against encapsulated bacterial infection like Neisseria and Meningococci.

The smaller peptides (C3a and C5a) are also very efficient at inducing inflammation. Not only do they attract granulocytes to the site of complement activation but also stimulation their degranulation. Finally, the later components (C5 – C9) can kill pathogens directly by causing cell lysis. In clinical terms, this is effective against encapsulated bacterial infection like Neisseria and Meningococci.

==COMPLEMENT INHIBITORS==

==COMPLEMENT INHIBITORS==