Difference between revisions of "Nuclear Transplantation/Cloning - Anatomy & Physiology"
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* Commonly used in mice to propagate required characteristics. | * Commonly used in mice to propagate required characteristics. | ||
* '''Embryonic stem cells''' are used as a source of '''totipotent nuclei''', which are capable of dividing into a range of new cells. | * '''Embryonic stem cells''' are used as a source of '''totipotent nuclei''', which are capable of dividing into a range of new cells. | ||
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* The cell source ,capable of replication in culture, can be stored by freezing and is therefore 'immortal' and able to produce many identical individuals. | * The cell source ,capable of replication in culture, can be stored by freezing and is therefore 'immortal' and able to produce many identical individuals. | ||
* Cloned individuals have a high percentage of developmental abnormalities. | * Cloned individuals have a high percentage of developmental abnormalities. | ||
| − | ** Often associated with [[ | + | ** Often associated with [[Joints Inflammatory - Pathology#Arthritis|Arthritis]] and [[Joints Inflammatory - Pathology|Joint problems]]. |
[[Category:Reproductive Technologies]] | [[Category:Reproductive Technologies]] | ||
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Revision as of 18:14, 1 December 2010
- Commonly used in mice to propagate required characteristics.
- Embryonic stem cells are used as a source of totipotent nuclei, which are capable of dividing into a range of new cells.
- These cells are fused with pre-ovulatory oocytes which have had their own haploid nucleus removed using electrofusion.
- Cells are artificially stimulated to the second meiotic division and begin embryonic development.
- The cell source ,capable of replication in culture, can be stored by freezing and is therefore 'immortal' and able to produce many identical individuals.
- Cloned individuals have a high percentage of developmental abnormalities.
- Often associated with Arthritis and Joint problems.