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Evaluation of diagnostic tests (view source)
Revision as of 16:19, 22 December 2010
, 16:19, 22 December 2010no edit summary
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| Gaussian (normal) distribution
| Gaussian (normal) distribution
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| Previously the most common method of selecting a cut-off
| Easy to use and understand
| Easy to use and understand
| Assumes test results are normally distributed<br />
| Assumes test results are normally distributed
Does not take the prevalence of disease into account<br />
Does not take the prevalence of disease into account
No scientific basis for cut-off
No scientific basis for cut-off
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|Percentile
|Percentile
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| Does not assume normality<br />
| Does not assume normality
Simple
Simple
| Does not take prevalence into account<br />
| Does not take prevalence into account
No scientific basis for cut-off
No scientific basis for cut-off
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| Risk factor
| Risk factor
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| Practical if risk factor is easy to measure
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|Requires knowledge of risk factors
PV+ may be low if risk factor is common in population
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| Therapeutic method
| Therapeutic method
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| Requires up to date knowledge of treatment methods
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| Predictive value method
| Predictive value method
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| Currently the most common method of selecting a cut-off
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| Scientific basis for selecting a cut-off
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Takes charachteristics of the test into account
Can be altered depending on objective of testing
| More complex method
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