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{{toplink
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|linkpage =Anaesthesia
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|linktext =Anaesthesia
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|maplink= Anaesthesia Content Map - WikiClinical
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|sublink1=Anaesthetic Drugs
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|subtext1=Anaesthetic Drugs
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|sublink2=Injectable Agents
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|subtext2=Injectable Agents
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|pagetype=Clinical
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}}
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Benzodiazepines are primarily anxiolytics, but do have sedative effects in man and sick animals. They also cause muscle relaxation and are anticonvulsants.
Benzodiazepines are primarily anxiolytics, but do have sedative effects in man and sick animals. They also cause muscle relaxation and are anticonvulsants.
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Diazepam may be given orally or intravenously. Intravenous administration gives a rapid onset of action. The drug is dissolved in propylene glycol, which may cause thrombophlebitis, pain on injection and cardiac arrhythmias.
Diazepam may be given orally or intravenously. Intravenous administration gives a rapid onset of action. The drug is dissolved in propylene glycol, which may cause thrombophlebitis, pain on injection and cardiac arrhythmias.
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As there are few cardiovascular side effect, diazepam is good for use as a premedicant. It can also be used with [[NMDA Antagonists|ketamine]] to induce and maintain anaethesia in the horse and in compromised small animals.
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As there are few cardiovascular side effect, diazepam is good for use as a premedicant. It can also be used with [[Dissociative Agents#Ketamine|ketamine]] to induce and maintain anaethesia in the horse and in compromised small animals.
===Midazolam===
===Midazolam===
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Inverse agonists act at the GABA receptor to close Cl<sup>-</sup> channels. They promote convulsions.
Inverse agonists act at the GABA receptor to close Cl<sup>-</sup> channels. They promote convulsions.
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[[Category:Sedatives and Tranquilisers]]
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[[Category:Injectable Anaesthetic Agents]]