Difference between revisions of "Inclusion Body Rhinitis"
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− | + | ===Inclusion body rhinitis=== | |
− | + | [[Image:Inclusion body rhinitis.jpg|right|thumb|100px|<small><center>Inclusion body rhinitis (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]] | |
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− | + | *[[Herpesviridae|'''Herpesviridae, porcine cytomegalovirus''']] | |
+ | *Disease of suckling piglets 1-5 wks of age | ||
+ | *Clinical signs: those associated with acute/subacute [[Rhinitis#Infectious causes of rhinitis|rhinitis]] (ie: serous nasal discharge, progressing to catarrhal or purulent discharge with time and secondary bacterial infections; sneezing; pyrexia), fever in young piglets (3-8wks old) | ||
+ | *May progress to [[Paranasal Sinuses Inflammatory - Pathology#Sinusitis|sinusitis]], otitis media or [[Lungs Inflammatory - Pathology#Infectious causes of pneumonia|pneumonia]] | ||
+ | *Morbitity high, mortality low | ||
+ | *Gross pathology - catarrhal discharge becoming purulent (secondary infection) | ||
+ | *Histology: | ||
+ | **Large basophilic [[Cellular Inclusions|intranuclear inclusion bodies]] in the surface and subepithelium of nasal and sinus glandular epithelium with lymphocytic infiltration of the mucosa | ||
+ | **Bursting of nucleus with cell necrosis and sloughing of necrotic epithelium | ||
+ | *Can develop viraemic stage, with inclusions and focal necrotising lesions in other organs eg: renal tubular epithelium | ||
+ | **Usually younger piglets, can die during this phase | ||
+ | *Usually resolves if uncomplicated but rhinitis may persist if secondary infection is present | ||
+ | *May persist in pulmonary macrophages | ||
− | == | + | ==Test yourself with the Infectious Causes of Inflammation Pathology Flashcards== |
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− | + | [[Infectious_Causes_of_Inflammation_Flashcards_-_Pathology|Infectious Causes of Inflammation Pathology Flashcards]] | |
− | + | [[Category:Herpesviridae]][[Category:Pig Viruses]][[Category:To_Do_-_Clinical/Viruses]] | |
− | + | [[Category:Respiratory_Viral_Infections]][[Category:Respiratory Diseases - Pig]] | |
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Revision as of 17:08, 15 February 2011
Inclusion body rhinitis
- Herpesviridae, porcine cytomegalovirus
- Disease of suckling piglets 1-5 wks of age
- Clinical signs: those associated with acute/subacute rhinitis (ie: serous nasal discharge, progressing to catarrhal or purulent discharge with time and secondary bacterial infections; sneezing; pyrexia), fever in young piglets (3-8wks old)
- May progress to sinusitis, otitis media or pneumonia
- Morbitity high, mortality low
- Gross pathology - catarrhal discharge becoming purulent (secondary infection)
- Histology:
- Large basophilic intranuclear inclusion bodies in the surface and subepithelium of nasal and sinus glandular epithelium with lymphocytic infiltration of the mucosa
- Bursting of nucleus with cell necrosis and sloughing of necrotic epithelium
- Can develop viraemic stage, with inclusions and focal necrotising lesions in other organs eg: renal tubular epithelium
- Usually younger piglets, can die during this phase
- Usually resolves if uncomplicated but rhinitis may persist if secondary infection is present
- May persist in pulmonary macrophages