Difference between revisions of "Inclusion Body Rhinitis"
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m (Text replace - "[[Nasal Cavity Inflammatory - Pathology" to "[[Rhinitis") |
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*[[Herpesviridae|'''Herpesviridae, porcine cytomegalovirus''']] | *[[Herpesviridae|'''Herpesviridae, porcine cytomegalovirus''']] | ||
*Disease of suckling piglets 1-5 wks of age | *Disease of suckling piglets 1-5 wks of age | ||
| − | *Clinical signs: those associated with acute/subacute [[ | + | *Clinical signs: those associated with acute/subacute [[Rhinitis#Infectious causes of rhinitis|rhinitis]] (ie: serous nasal discharge, progressing to catarrhal or purulent discharge with time and secondary bacterial infections; sneezing; pyrexia), fever in young piglets (3-8wks old) |
*May progress to [[Paranasal Sinuses Inflammatory - Pathology#Sinusitis|sinusitis]], otitis media or [[Lungs Inflammatory - Pathology#Infectious causes of pneumonia|pneumonia]] | *May progress to [[Paranasal Sinuses Inflammatory - Pathology#Sinusitis|sinusitis]], otitis media or [[Lungs Inflammatory - Pathology#Infectious causes of pneumonia|pneumonia]] | ||
*Morbitity high, mortality low | *Morbitity high, mortality low | ||
Revision as of 17:08, 15 February 2011
Inclusion body rhinitis
- Herpesviridae, porcine cytomegalovirus
- Disease of suckling piglets 1-5 wks of age
- Clinical signs: those associated with acute/subacute rhinitis (ie: serous nasal discharge, progressing to catarrhal or purulent discharge with time and secondary bacterial infections; sneezing; pyrexia), fever in young piglets (3-8wks old)
- May progress to sinusitis, otitis media or pneumonia
- Morbitity high, mortality low
- Gross pathology - catarrhal discharge becoming purulent (secondary infection)
- Histology:
- Large basophilic intranuclear inclusion bodies in the surface and subepithelium of nasal and sinus glandular epithelium with lymphocytic infiltration of the mucosa
- Bursting of nucleus with cell necrosis and sloughing of necrotic epithelium
- Can develop viraemic stage, with inclusions and focal necrotising lesions in other organs eg: renal tubular epithelium
- Usually younger piglets, can die during this phase
- Usually resolves if uncomplicated but rhinitis may persist if secondary infection is present
- May persist in pulmonary macrophages