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| − | [[Image:Sporotrichosis horse.jpg|thumb|right|150px|Sporotrichosis in a horse -Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath]] | + | *Caused by [[Sporothrix schenckii|''Sporothrix schenckii'']] |
| − | [[Image:Sporotrichosis cigar cells.jpg|thumb|right|150px|Sporotrichosis cigar shaped cells -Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath]]
| + | *Cutaneous, may involve lymhatic vessels or disseminate |
| − | *''Sporothrix schenckii'' | + | *Occurs in horses, cattle, cats and dogs |
| | + | *Grossly: |
| | + | **Ulcerated cutaneous nodules |
| | + | **Fistulas may form |
| | + | *Microscopically: |
| | + | **Hard to find ovoid to elongated organisms |
| | + | **More numerous in cats |
| | + | *Exudate may be infectious to humans if comes into contact with wounds |
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| − | *Occurs in soil, wood and vegetation
| + | ==Test yourself with the Subcutaneous Mycoses Flashcards== |
| − | **Saprophyte of both decaying and healthy vegetation
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| − | *Worldwide
| + | [[Subcutaneous_Mycoses_-_Flashcards#Sporotrichosis|Sporotrichosis Flashcards]] |
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| − | *Exogenous infections through wounds
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| − | *Sporadic infections
| + | [[Category:Subcutaneous Mycoses]][[Category:To Do - Fungi]] |
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| − | *Non-contageous
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| − | *Causes subcutaneous nodules or granulomas
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| − | **Nodules ulcerate discharging pus
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| − | *Spread via the [[Lymphatic System - Anatomy & Physiology|lymphatics]]
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| − | *The [[Bones and Cartilage - Anatomy & Physiology|bones]] and viscera can be involved which terminates in mortality
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| − | **This is rare
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| − | **Reported in dogs and horses
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| − | *Affects dogs, horses, cats, monkeys, mules, camels, donkeys, cattle, fowl and rodents
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| − | **Most commonly seen in horses as an ascending lymphocutaneous infection of the legs
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| − | **Can be confused with [[Subcutaneous Mycoses#Epizootic Lymphangitis|epizootic lymphangitis]] in horses
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| − | *Single cell, cigar shaped
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| − | **Usually found within [[Neutrophils|neutrophils]]
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| − | **Yeast cell clusters with peripheral eosinophilic rays can be seen in tissue sections
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| − | *Stained using PAS, Gram stain (positive), fluorescent antibody and Calcofluor White
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| − | *Latex agglutination and immunodiffusion serology can be performed
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| − | *Grows on Blood agar and Sabouraud's Dextrose agar in one to three weeks
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| − | **At 37°C:
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| − | ***Colonies are smooth, cream to tan coloured and soft
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| − | ***No mycelium can be seen
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| − | **At 25°C to 27°C:
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| − | ***Colonies turn from white and soft to tan to brown to black
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| − | ***Leathery, wrinkled and coarse
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| − | ***Mycelium can be seen as branching septate hyphae
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| − | ***Conidiospores can also be seen
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| − | *Potassium iodide treatment orally
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| − | **[[Antifungal Drugs#Flucytosine|5-fluorocytosine]] and [[Antifungal Drugs#Polyene Antifungals|amphotericin B]] can also be used[[Category:Subcutaneous_Mycoses]]
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| − | [[Category:To_Do_-_Fungi]] | |