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*Affects puppies of collies and shetland sheepdogs from 8 weeks of age
 
*Affects puppies of collies and shetland sheepdogs from 8 weeks of age
 
*Lesions - vesiculating dermatitis
 
*Lesions - vesiculating dermatitis
 
**Face, lips, external ears, later distal extremities
 
**Face, lips, external ears, later distal extremities
 
*Microscopically: interface dermatitis and basal cell degeneration of epidermis and follicular wall, atrophy of follicles, epidermal vesicles and pustules, dermal scarring
 
*Microscopically: interface dermatitis and basal cell degeneration of epidermis and follicular wall, atrophy of follicles, epidermal vesicles and pustules, dermal scarring
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*Hereditary in Collies and Shetland sheepdgs
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*Lesions resemble [[Muscles Inflammatory - Pathology#Canine polymyositis|canine polymyositis]]
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*Also degeneration of blood vessels -> muscle [[Muscles Degenerative - Pathology#Ischaemia|microinfarcts]]
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*Usually generalised but temporalis and other masticatory muscles may be involved the most
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*Microscopically: inclusion bodies in endothelial cells
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*Best place for biopsy is anterior and most superficial temporalis muscle
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*Also involves skin, may involve the oesophagus
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[[Category:Integumentary System - Autoimmune Reactions]]
 
[[Category:Integumentary System - Autoimmune Reactions]]
Author, Donkey, Bureaucrats, Administrators
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