Difference between revisions of "Bones Metabolic - Pathology"

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===Fluorine poisoning===
+
===[[Fluorine Poisoning]]===
  
*F is widespread in nature
 
*Pastures may be contaminated by industrial processes (e.g. brick manufacture)
 
*'''Acute poisoning''':
 
**Gastroenteritis
 
**Nephrosis
 
*'''Chronic poisoning''':
 
**''Dental abnormalities''
 
***Intoxication during teeth development
 
***Foci of poor enamel formation - yellow, dark brown/black, chalky
 
***Irregular wear of teeth, chip easily
 
**''Osteodystrophy = Fluorosis''
 
***Generalised skeletal disturbance
 
***Most affected are metatarsals and mandibles
 
***Periosteal hyperostosis + endosteal bone resorption -> thickened bones with enlarged marrow cavities
 
 
[[Category:Bones - Metabolic Pathology]]
 
[[Category:Toxicology]]
 
  
 
===Lead poisoning===
 
===Lead poisoning===

Revision as of 18:57, 27 February 2011

Hypovitaminosis A

Hypervitaminosis A

Hypervitaminosis D

Fluorine Poisoning

Lead poisoning

  • Lead can bind to mineral portion of bone and cartilage
  • In young animals ingesting large dose at once
    • -> Lead induced malfunction of osteoclasts
    • -> Transverse band of increased density on radiographs of metaphysis = "lead line" = growth retardation lattice