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| *Most common type of physeal fracture in small animals and the proximal femur is the most common site | | *Most common type of physeal fracture in small animals and the proximal femur is the most common site |
| *In horses, physeal dysplasia is synonymus with [[Physitis|physitis]] | | *In horses, physeal dysplasia is synonymus with [[Physitis|physitis]] |
− | | + | *[[More about Physeal dysplasia]] |
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− | '''More about Physeal dysplasia'''
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− | *Also seen in the coypu with minimal trauma
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− | *Femoral head physes contribute 30-40% of longitudinal growth of the femur in small animals
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− | *Slipped epiphysis -> Salter-Harris type I where only the physis is involved
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− | **Most common type of physeal fracture in small animals and the proximal femur is the most common site
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− | **In traumatic cases, the fracture crosses through mutiple zones of the physis, with chondrocytes maintaining their linear arrangement on both sides of the fracture site for 1-4d following trauma
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− | *Slipped capital femoral epiphysis – seen in humans, mainly adolescent boys, autosominal dominant with variable penetrance
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− | In cats:
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− | *'''[Physeal dysplasia with slipped capital femoral epiphysis in 13 cats. Craig LE. Vet Path (2001) 38 92-7]'''
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− | **Age 12-21months
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− | **90% males
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− | **Often obese, lots of Siamese cats
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− | **Normal growth plates close at 7-9mths so these physes should have been closed
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− | **Histology – physeal dysplasia with persistence of an open, disorganized growth plate
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− | ***Wide physis, necrotic cartilage at the cleavage site
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− | ***Irregular clusters of chondrocytes separated by abundant chondroid matrix. Similar lesions in femoral neck.
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− | **No necrosis of the femoral head, although there is usually a small areas of peripheral attachment at the perichondral fibrocartilagenous complex – could provide some vacularization **The ligamentum teres provides no blood supply to the femoral head
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− | **Clusters of chondrocytes present on either side of the cleavage site
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− | **Differs from [[Joints Developmental - Pathology#Osteochondrosis|osteochondrosis]] by:
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− | ***More diffuse affecting the whole physis (in OC – focal failure of endochondral ossification)
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− | ***Chondrocytes are arranged in disorganized clusters rather than parallel rows
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− | ***The cat breeds have not been selected for rapid growth
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− | **Insulin may have a role to play – most of the cats were obese....Similar deal to horse osteochondrosis
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| [[Category:Bones - Degenerative Pathology]] | | [[Category:Bones - Degenerative Pathology]] |