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==Changes to normal structure==
===Damage to Periosteum===
*Invokes a hyperplastic reaction of the inner layer
*Is painful
*Exostoses can remodel or remain
Lifting of periosteum causes new bone formation below
Circumferential incision (e.g. during [[Bones Fractures - Pathology|fracture]])
*Longitudinal bone growth results
*May be only on one side where periosteum is damaged
**Used by surgeons to treat [[Angular Limb Deformity|angular limb deformities]]
===Physis (Growth plate)===
*Site of many '''congenital''' or '''nutritional''' bone diseases in the growing animal
*'''Open''' in neonates and growing animals
**Chondrocyte proliferation balances cell maturation and death
*'''Closes and ossifies''' at maturity
**Regulated by androgens
*If growth teporarily stops -> layer of bone seals the growth plate -> moves into metaphysis when growth resumes -> forms '''Harris lines'''
==Test yourself with the Bone and Cartilage Pathology Flashcards==
[[Bones_and_Cartilage_Flashcards_-_Pathology|Bones and Cartilage Flashcards]]
[[Category:Bones - Pathology|A]]