Bone Response to Damage

Changes to normal structure

Damage to Periosteum

• Invokes a hyperplastic reaction of the inner layer
• Is painful
• Exostoses can remodel or remain

Lifting of periosteum causes new bone formation below

Circumferential incision (e.g. during fracture)

• Longitudinal bone growth results
• May be only on one side where periosteum is damaged
  • Used by surgeons to treat angular limb deformities

Physis (Growth plate)

• Site of many congenital or nutritional bone diseases in the growing animal
• Open in neonates and growing animals
  • Chondrocyte proliferation balances cell maturation and death
• Closes and ossifies at maturity
  • Regulated by androgens
• If growth teporarily stops -> layer of bone seals the growth plate -> moves into metaphysis when growth resumes -> forms Harris lines

Test yourself with the Bone and Cartilage Pathology Flashcards

Bones and Cartilage Flashcards