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− | ==Degeneration==
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− | [[Image:Degenerate muscle fibres.jpg|right|thumb|100px|<small><center>Degenerate muscle fibres (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]
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− | *Different types of degeneration
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− | *May, or may not, be reversible
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− | *Cloudy swelling, hydropic, vacuolar, granular and fatty change
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− | *Occur following many different types of insult and are usually '''segmental'''
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− | *If regeneration does not occur after formation of small vacuoles, [[Muscles Degenerative - Pathology#Necrosis|necrosis]] follows
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− | **Vacuolation -> floccular degeneration -> granular degeneration -> [[Hyaline Degeneration|hyaline]] and [[Zenker Degeneration - Pathology|Zenker’s degeneration]]
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− | *[[Hydropic Degeneration#Vacuolar Degeneration|'''Vacuolar degeneration''']]:
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− | **Due to swelling of organelles or due to glycogen or fat accumulation
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− | **May be caused by hypokalaemia, hyperkalaemia or necrosis
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− | *Histologically:
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− | **Swollen
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− | **Hypereosinophilic
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− | **Lost cross striations
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− | ===[[Muscle Calcification]]===
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− | ===[[Muscle Ossification]]===
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− | ===[[Muscle Pigmentation]]===
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− | ==Nutritional myopathy==
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− | ===[[White Muscle Disease|White muscle disease]]===
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− | ==Exertional myopathies==
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− | *Caused by intensive and exhaustive activity of major muscle masses
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− | *Glycogen used up -> local heat and lactic acid -> muscle degeneration
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− | *Other forms include '''capture myopathy''', racing greyhounds, sheep chased by dogs
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− | ===[[Equine Rhabdomyolysis]]===
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− | ===[[Porcine Stress Syndrome]]===
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− | ==Neuromuscular junction diseases==
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− | ===Aquired myasthenia gravis===
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− | *See [[Myasthenia Gravis|congenital MG]]
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− | ===[[Botulism]]===
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− | ==Circulatory disturbances==
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− | ===[[Muscle Congestion]]===
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− | ===[[Muscle Ischaemia]]===
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− | ==[[Muscle Trauma]]==
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| [[Category:Musculoskeletal System - Pathology]] | | [[Category:Musculoskeletal System - Pathology]] |