Difference between revisions of "Porcine Stress Syndrome"
Jump to navigation
Jump to search
(Created page with "*'''Malignant hyperthermia''' *Pigs, dogs, humans *Possibly a cellular defect resulting in high intacellular calcium ion concentration **-> Activates myofibrillar ATPase -> rapid...") |
|||
| Line 7: | Line 7: | ||
*Histologically: | *Histologically: | ||
**Segmental hypercontraction | **Segmental hypercontraction | ||
| − | **Monophasic, multifocal [[ | + | **Monophasic, multifocal [[Muscle Necrosis|segmental necrosis]] |
*Inherited | *Inherited | ||
*Triggered by halothane anaesthesia, stress of handling, transportation or slaughter | *Triggered by halothane anaesthesia, stress of handling, transportation or slaughter | ||
Revision as of 18:29, 3 March 2011
- Malignant hyperthermia
- Pigs, dogs, humans
- Possibly a cellular defect resulting in high intacellular calcium ion concentration
- -> Activates myofibrillar ATPase -> rapid intracellular glycolysis -> increase in body heat -> denature protein -> cell death -> leakage of cellular content -> oedema
- Grossly:
- Muscles are pale, soft and exudative
- Histologically:
- Segmental hypercontraction
- Monophasic, multifocal segmental necrosis
- Inherited
- Triggered by halothane anaesthesia, stress of handling, transportation or slaughter