Difference between revisions of "CNS Degenerative Diseases - Pathology"

Revision as of 14:11, 8 March 2011

(CDS)

CDS causes signs of senility.
Increasing numbers of dogs and cats are suffering from CDS.
- Prevalence is similar to that seen in humans: an 85 year-old human is roughly equivalent to a 15 year-old cat, and a 13-14 year-old dog.
  - Aging in dogs id breed specific.

@@ Line 1: / Line 1: @@
-#redirect[[:Category:Central Nervous System - Degenerative Pathology]]
+==Equine [[Laryngeal Hemiplegia]]==
+==[[Lysosomal Storage Disease]] ==
+==[[Cognitive Dysfunction Syndrome]] ==
+(CDS)
+* CDS causes signs of senility.
+* Increasing numbers of dogs and cats are suffering from CDS.
+** Prevalence is similar to that seen in humans: an 85 year-old human is roughly equivalent to a 15 year-old cat, and a 13-14 year-old dog.
+*** Aging in dogs id breed specific.
+===Pathology===
+* A number of changes are seen in the brains of geriatric animals which may cause the signs of CDS.
+** Vascular insufficiency leads to:
+*** Hypoxia
+*** Increased free redical production
+*** Deposition of amyloid plaques
+*** Modification of other brain proteins
+===Treatment===
+* There are no published studies related to treatment of CDS in animals.
+* Potential therapies include:
+** Dietary modification
+*** Diets are enriched with antioxidants, vitamin E, beta-carotene and essential fatty acids.
+** Environmental stimulation
+** Drugs
+*** Selegiline
+*** Propentofylline
+*** Nicergoline
+[[Category:Central Nervous System - Degenerative Pathology]]