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| − | ==Overview== | + | == Introduction == |
| − | Disease caused by the parasite [[Cryptosporidium|cryptosporidium]].
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| | + | This is a '''zoonotic''', diarrhoea- causing, disease of cattle and other domestic livestock caused by the parasite [[Cryptosporidium|cryptosporidium]].It is a protozoan parasite that inhabits crypt cells of the intestine. Transmission of the disease is faeco- oral. The disease is sever in humans and can be fatal in the immunocompromised. It causes severe sickness and diarrhoea for up to two weeks.<br> |
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| − | ==Diagnosis==
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| − | *Faecal smear
| + | == Clinical Signs == |
| − | **Ziehl-Neelson (ZN) stain
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| − | **Oocysts stain red against a blue/green background
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| − | *Immunoassays
| + | Often seen in adolescent calves, may present as a sudden outbreak or as sporadic disease. Animals may have weight loss and and appear dull and depressed. Diarrhoea will be profuse and watery and may appear green/ black. |
| − | **Detect oocysts in faeces
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| − | ==Control==
| + | <br> |
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| − | *Isolate/quarantine bought-in calves
| + | == Diagnosis == |
| − | **Treat if signs of [[Diarrhoea|diarrhoea]] present
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| − | *Good hygiene, adequate bedding and disinfection of calf pens is important
| + | Clinical signs and age of cattle will provide a presumptive diagnosis. A faecal smear with '''Ziehl-Neelson''' (ZN) stain is diagnostic and if cryptosporidium is present then oocysts stain red against a blue/green background. Immunoassayscan also be performed to detect oocysts in faeces. |
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| − | *Prevention/treatment
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| − | **Halofuginone
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| − | ***Halocur or Intervet
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| − | ***Oral dosage
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| − | ==Villus Atrophy in Enteritis== | + | == Control == |
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| − | * Affects calf, lamb, piglet, kitten.
| + | Isolate/quarantine bought-in calves maintain good hygiene by providing adequate bedding and disinfecting calf pens. |
| − | * Increasingly important as part of the neonatal [[Diarrhoea|diarrhoea]] complex in calves.
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| − | * Zoonosis.
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| − | ====Pathology====
| + | If diarrhoea is present and cryptosporidium has been detected then treat with halofuginon, trade names Halocur or Intervet. This treatment is given orally. |
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| − | =====Gross=====
| + | <br> |
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| − | * Intestines diffusely reddened, with fluid contents.
| + | [[Category:To_Do_-_Review]] |
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| − | =====Histological=====
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| − | * Tiny parasites on surface of epithelium.
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| − | * Villus atrophy and fusion.
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| − | * Iinflammation (mainly lymphoid) in crypts and lamina propria.
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| − | [[Category:To_Do_-_Clinical]] | |