Difference between revisions of "Pyelonephritis"

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caused by [[Corynebacterium renale]]
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*Pyelonephritis is inflammation of the renal pelvis and parenchyma.
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*Most often occurs in cows and sows.
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*Main predisposing factor is urinary stasis which can occur due to pregnancy, following service in the sow, following uterine and bladder prolapse or the use of catheters in small animals.
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*Usually occurs due to ascending bacterial infection from the lower urinary tract.
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'''Gross pathology'''
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*Kidney may be swollen with external patchy congestion.
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*The medulla has streaks of inflammatory debris that extend into the cortex.
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*The renal pelvis as well as the ureters are dilated and contain pus.
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*In chronic cases, the kidney is shrunken, distorted and has gray patches among a diffuse, tan discolouration.  The medulla has fibrous tracts that run into the capsule.
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'''Histopathology'''
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*Dilated tubules filled with [[Neutrophils|neutrophils]].
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*Presences of bacteria within the tubules.
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*Necrosis of the pelvic epithelium and collecting tubules.
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*In chronic cases, presence of fibrosis within the medulla as well as ascending fibrous tracts into the cortex.
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'''Examples'''
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*''[[Corynebacterium renale]]'' in cattle and ''Eubacterium suis'' in pigs.
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'''Definitons'''
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*''Pyelitis'' - infection involving the renal pelvis alone.
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*''Pyonephritis'' - suppuration of the whole kidney.
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[[Category:Tubulointerstitial Disease]]
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[[Category:To Do - Urinary]]

Latest revision as of 10:57, 13 April 2011

  • Pyelonephritis is inflammation of the renal pelvis and parenchyma.
  • Most often occurs in cows and sows.
  • Main predisposing factor is urinary stasis which can occur due to pregnancy, following service in the sow, following uterine and bladder prolapse or the use of catheters in small animals.
  • Usually occurs due to ascending bacterial infection from the lower urinary tract.

Gross pathology

  • Kidney may be swollen with external patchy congestion.
  • The medulla has streaks of inflammatory debris that extend into the cortex.
  • The renal pelvis as well as the ureters are dilated and contain pus.
  • In chronic cases, the kidney is shrunken, distorted and has gray patches among a diffuse, tan discolouration. The medulla has fibrous tracts that run into the capsule.

Histopathology

  • Dilated tubules filled with neutrophils.
  • Presences of bacteria within the tubules.
  • Necrosis of the pelvic epithelium and collecting tubules.
  • In chronic cases, presence of fibrosis within the medulla as well as ascending fibrous tracts into the cortex.

Examples

Definitons

  • Pyelitis - infection involving the renal pelvis alone.
  • Pyonephritis - suppuration of the whole kidney.