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Also known as: '''''BSE — Bovine Spongiform Encephalopathy''''', '''''TSE — Transmissible Spongiform Encephalopathy'''''', '''''Mad Cow Disease''''', , '''''Scrapie — a transmissble prion affecting sheep that causes non-febrile neurological disease''''', '''''PrP - (Prion protein) proteinaceous infectious particle''''', '''''PrP<sup>ab</sup> — Abnormal Prion Protein''''',  '''''PrP<sup>res</sup> —  Resistant Prion Protein'''''',  '''''PrP<sup>sc</sup> —  Scrapie Prion Protein'''''  
 
Also known as: '''''BSE — Bovine Spongiform Encephalopathy''''', '''''TSE — Transmissible Spongiform Encephalopathy'''''', '''''Mad Cow Disease''''', , '''''Scrapie — a transmissble prion affecting sheep that causes non-febrile neurological disease''''', '''''PrP - (Prion protein) proteinaceous infectious particle''''', '''''PrP<sup>ab</sup> — Abnormal Prion Protein''''',  '''''PrP<sup>res</sup> —  Resistant Prion Protein'''''',  '''''PrP<sup>sc</sup> —  Scrapie Prion Protein'''''  
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[[File:Histology BSE.jpg]]
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==Introduction==
 
==Introduction==
 
BSE was first recognised in the United Kingdom in 1986 after a huge epidemic in the UK involving over 100,000 diseased cattle.  With the exception of France and Portugal, the number of infected animals in other countries has remained low. The disease is now worldwide and has occurred in Europe, Asia, Middle East and North America.  
 
BSE was first recognised in the United Kingdom in 1986 after a huge epidemic in the UK involving over 100,000 diseased cattle.  With the exception of France and Portugal, the number of infected animals in other countries has remained low. The disease is now worldwide and has occurred in Europe, Asia, Middle East and North America.  
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