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Chicken Anaemia Virus Disease Flashcards (view source)
Revision as of 10:19, 29 June 2011
, 10:19, 29 June 2011no edit summary
*Blue wing disease
*Blue wing disease
|l1=Chicken Anaemia Virus Disease#Introduction
|l1=Chicken Anaemia Virus Disease#Introduction
|q2=Which virus causes Chicken Anaemia Virus Disease and what are it's properties?
|q2=Which virus causes ''Chicken Anaemia Virus Disease'' and what are it's properties?
|a2=
|a2=
Chicken anaemia virus (CAV):
''Chicken anaemia virus'' (CAV):
*non-enveloped icosahedral single stranded DNA (ssDNA) virus
*Non-enveloped icosahedral single stranded DNA (ssDNA) virus
*23-25 nm diameter
*23-25 nm diameter
*Small circular genome of negative sense
*Small circular genome of negative sense
*Very hardy and resistant to high temperatures, acidic pH (pH3), chloroform and commercial disinfectants.
*Very hardy and resistant to high temperatures, acidic pH (pH3), chloroform and commercial disinfectants.
*It is morphologically and antigenically different to other circoviruses such as ''Porcine circovirus'' (PCV) and ''Psittacine beak and feather disease virus'' (PBFDV).
*Morphologically and antigenically different to other circoviruses such as ''Porcine circovirus'' (PCV) and ''Psittacine beak and feather disease virus'' (PBFDV).
|l2=Chicken Anaemia Virus Disease#Introduction
|l2=Chicken Anaemia Virus Disease#Introduction
|q3= ?
|q3=What family does the ''Chicken anaemia virus'' (CAV) belong to?
|a3=Circoviridae
|a3=Circoviridae
|l3= #
|l3=Chicken Anaemia Virus Disease#Introduction
|q4= ?
|q4=What chemicals destroy the virus?
|a4= CAV can be destroyed with hypochlorite and iodophor and formalin can reduce its infectivity.
|a4=
|l4=
*Hypochlorite and iodophor
Formalin only reduces its infectivity.
|l4=Chicken Anaemia Virus Disease#Introduction
|q5=How many proteins does CAV produce?
|a5=
Three:
*Non-enveloped icosahedral single stranded DNA (ssDNA) virus
*VP1 (52kDA) - structural protein; intracellular form of the capsid protein
*VP2 (24 kDA) - found in small amounts in the purified virus
(Vaccines need to contain both of these to be antigenic).
*VP3 (14 kDA) - involved in apoptosis (programmed and controlled cell death with no lysis of the cell. Causes apoptosis of infected stem cells in the bone marrow (BM). Sequential damage to BM inhibits the production of red blood cells (RBC), white blood cells (WBC), lymphoid tissue and platelets
Due to its apoptotic properties VP3 has the potential to be an anti-cancer agent
|l5=Chicken Anaemia Virus Disease#Introduction
|q6=What family does the ''Chicken anaemia virus'' (CAV) belong to?
|a6=Circoviridae
|l6=Chicken Anaemia Virus Disease#Introduction
|q7=What chemicals destroy the virus?
|a7=
*Hypochlorite and iodophor
Formalin only reduces its infectivity.
|l7=Chicken Anaemia Virus Disease#Introduction
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