Difference between revisions of "Porcine Stress Syndrome"
Jump to navigation
Jump to search
| Line 13: | Line 13: | ||
[[Category:Muscles - Developmental Pathology]] | [[Category:Muscles - Developmental Pathology]] | ||
| − | [[Category:To Do - | + | [[Category:To Do - Jaimie Meagor]] |
Revision as of 07:48, 1 July 2011
- Malignant hyperthermia
- Pigs, dogs, humans
- Possibly a cellular defect resulting in high intacellular calcium ion concentration
- -> Activates myofibrillar ATPase -> rapid intracellular glycolysis -> increase in body heat -> denature protein -> cell death -> leakage of cellular content -> oedema
- Grossly:
- Muscles are pale, soft and exudative
- Histologically:
- Segmental hypercontraction
- Monophasic, multifocal segmental necrosis
- Inherited
- Triggered by halothane anaesthesia, stress of handling, transportation or slaughter