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===Pathology===
 
===Pathology===
 
*Damage to prickle cells (stratum spinosum).
 
*Damage to prickle cells (stratum spinosum).
*Appears as accumulation of fluid within epithelium, quickly erodes leaving hyperaemic [[stratum germinativum]].
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*Appears as accumulation of fluid within epithelium, quickly erodes leaving hyperaemic stratum germinativum.
 
*Heals by proliferation of new cells, so long as infection does not continue.  
 
*Heals by proliferation of new cells, so long as infection does not continue.  
 
===Pathogenesis===
 
===Pathogenesis===
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#Ingestion of hot food (corrosive liquids)
 
#Ingestion of hot food (corrosive liquids)
 
#Systemic viral diseases. ''e.g'':
 
#Systemic viral diseases. ''e.g'':
##[[Foot and Mouth Disease Virus|Foot and Mouth disease]] - ruminants and pigs
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##[[Foot and Mouth Disease|Foot and Mouth disease]] - ruminants and pigs
##[[Vesicular stomatitis]] - horse, pigs, cattle
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##[[Vesicular Stomatitis Virus]] - horse, pigs, cattle
##[[Vesicular exanthema]] - pigs  
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##[[Vesicular Exanthema - Pig|Vesicular Exanthema]] - pigs  
 
 
 
N.B. All are indistinguishable from FMD clinically.
 
N.B. All are indistinguishable from FMD clinically.
   −
===[[Foot and Mouth Disease (FMDV)]]===
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===[[Foot and Mouth Disease|Foot and Mouth Disease (FMDV)]]===
       
===[[Swine Vesicular Disease]]===
 
===[[Swine Vesicular Disease]]===
*May produce vesicles in mouth that are indistinguishable from foot and mouth disease
  −
*Swine vesicular disease produces sporadic large outbreaks
  −
**Approximately 5% have lesions in mouth, foot lesions much more common
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===Vesicles in dogs===
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===[[Oral Vesicles in Dogs]]===
*Vesicles in mouth are often caused by hot food - especially in dogs. 
  −
*Can produce quite big vesicles, but will heal. 
  −
*No major problems associated with vesicles on [[Oral Cavity - Tongue - Anatomy & Physiology|tongue]] in dogs (except if due to drinking battery acid, but this also produces vomiting).
       
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