Difference between revisions of "Small Animal Dermatology Q&A 16"

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*cystic or dilated hair follicles. <br>
 
*cystic or dilated hair follicles. <br>
 
As hairs regrow, they grow more slowly and are often deformed. This disorder has been seen in cats with blue or cream colored coats.
 
As hairs regrow, they grow more slowly and are often deformed. This disorder has been seen in cats with blue or cream colored coats.
|l1=Colour Dilution Alopecia
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|l1=
 
|q2=How is this disorder treated?
 
|q2=How is this disorder treated?
 
|a2=
 
|a2=
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As a result, excessive grooming and harsh shampoos should be avoided. It is important to control the recurrent bacterial pyodermas associated with this disorder. <br><br>
 
As a result, excessive grooming and harsh shampoos should be avoided. It is important to control the recurrent bacterial pyodermas associated with this disorder. <br><br>
 
Affected dogs will continue to lose hair, and many are alopecic by 2–3 years of age.
 
Affected dogs will continue to lose hair, and many are alopecic by 2–3 years of age.
|l2=Colour Dilution Alopecia#Treatment
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|l2=
 
|q3=What are the most common histological findings?
 
|q3=What are the most common histological findings?
 
|a3=
 
|a3=
 
Common histological findings show melanin clumping in the epidermal and follicular basal cells, macromelanosomes in the hair shafts or hair bulbs, and follicular dysplasia. <br><br>
 
Common histological findings show melanin clumping in the epidermal and follicular basal cells, macromelanosomes in the hair shafts or hair bulbs, and follicular dysplasia. <br><br>
 
The melanin clumping and macromelanosomes are key findings for diagnosis of this disease.
 
The melanin clumping and macromelanosomes are key findings for diagnosis of this disease.
|l3=Colour Dilution Alopecia#Diagnosis
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|l3=Pigmentation - Pathology#Melanin
 
</FlashCard>
 
</FlashCard>
  

Revision as of 15:46, 21 July 2011


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A 2-year-old blue doberman pinscher dog was referred for the problem of an ‘endocrine alopecia’ of unknown etiology. Previous diagnostic tests were normal or negative and included: skin scrapings, dermatophyte culture, complete blood count, urinalysis, serum chemistry panel, thyroid hormone evaluation, low-dose dexamethasone suppression test, and surgical neutering. Dermatological examination reveals a thin hair coat, nodular-like hair follicles, comedones, bacterial pyoderma, and scaling. All of the other littermates are similarly affected.


Question Answer Article
What is the most likely diagnosis, and what is the cause? [[|Link to Article]]
How is this disorder treated? [[|Link to Article]]
What are the most common histological findings? Link to Article


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