Changes

|a1=  

|a1=  

*Freshwater

*Freshwater

* Saltwater  

*Saltwater  

*Aquarium fish

*Aquarium fish

|l1= Mycobacteriosis - Fish#Introduction

|l1= Mycobacteriosis - Fish#Introduction

*haemorrhagic lesions, erosion and scale loss on skin and fins,  

*haemorrhagic lesions, erosion and scale loss on skin and fins,  

*organomegaly

*organomegaly

* lordosis

*lordosis

* cachexia

*cachexia

* exophthalmia

*exophthalmia

* loss of pigmentation, and pale and cystic gills.  

*loss of pigmentation, and pale and cystic gills.  

Behavioural signs include:

Behavioural signs include:

* cessation of feeding,  

*cessation of feeding,  

*lethargy,  

*lethargy,  

*swimming near the surface

*swimming near the surface

Necrotising infections in humans are caused by:

Necrotising infections in humans are caused by:

*''M. marinum ''

*''M. marinum ''

*''M. fortuitum''   

*''M. fortuitum''   

|l4= Mycobacteriosis - Fish#Introduction

|l4= Mycobacteriosis - Fish#Introduction

|q5= What methods help to diagnose ''mycobacterial'' infections?

|q5= What methods help to diagnose ''mycobacterial'' infections?

* PCR  

* PCR  

* DNA probes- in situ hybridisation

* DNA probes- in situ hybridisation

*Antibody-based methods  

*Antibody-based methods  

|l5= Mycobacteriosis - Fish #Diagnosis

|l5= Mycobacteriosis - Fish#Diagnosis

|q6= What pathology is associated with sub acute form of Mycobacteriosis in fish?

|q6= What pathology is associated with sub acute form of Mycobacteriosis in fish?

|a6=

|a6=

|q7= What pathology is associated with the chronic proliferative form of Mycobacteriosis in fish?

|q7= What pathology is associated with the chronic proliferative form of Mycobacteriosis in fish?

|a7=

|a7=

* Soft granulomas  - with four distinguishable layers; a central caseous necrosis, (with or without nuclear debris), spindle-shaped epithelioid cells, eosinophilic, flattened, epithelioid cells and then a fine fibrous connective tissue encircling to form a thin capsule.

* '''Soft granulomas''' - with four distinguishable layers:

*Hard granulomas - composed of epithelioid cells encapsulated by fibrous connective tissue with or without calcification.

**central caseous necrosis(with or without nuclear debris)

**spindle-shaped epithelioid cells

**eosinophilic, flattened, epithelioid cells  

**fine fibrous connective tissue forming a thin capsule

*'''Hard granulomas''' - composed of epithelioid cells encapsulated by fibrous connective tissue with or without calcification.

|l7= Mycobacteriosis - Fish # Pathology

|l7= Mycobacteriosis - Fish # Pathology

|q8= How can Mycobacteriosis in fish be treated?

|q8= How can Mycobacteriosis in fish be treated?