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Equine Internal Medicine Q&A 05 (view source)
Revision as of 13:59, 22 August 2011
, 13:59, 22 August 2011no edit summary
|a1=
|a1=
The most likely diagnosis is glomerulonephritis with renal failure.
The most likely diagnosis is glomerulonephritis with renal failure.
|l1=
|l1=Glomerulonephritis
|q2=What is the presumed pathological mechanism of the disease?
|q2=What is the presumed pathological mechanism of the disease?
|a2=The presumed pathological mechanism of glomerulonephritis is persistent immune complex deposition or in situ formation in the glomerulus.<br><br>
|a2=The presumed pathological mechanism of glomerulonephritis is persistent immune complex deposition or in situ formation in the glomerulus.<br><br>
In the horse the deposits are most severe within the glomerular capillary walls. <br>
In the horse the deposits are most severe within the glomerular capillary walls. <br>
These deposits cause activation of soluble and cellular mediators within the kidney, causing protein loss in the urine, decreased glomerular filtration and renal failure.
These deposits cause activation of soluble and cellular mediators within the kidney, causing protein loss in the urine, decreased glomerular filtration and renal failure.
|l2=
|l2=Glomerulonephritis
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