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<FlashCard questions="11">
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<FlashCard questions="15">
|q1=What causes ''Blue eye disease '' in pigs?
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|q1=What causes Blue eye disease in pigs?
|a1= ''Blue-eye paramyxovirus (BEP'' - a negative sense single stranded RNA(ssRNA) virus.
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|a1= Blue-eye paramyxovirus (BEP) - a negative sense single stranded RNA (ssRNA) virus.
|l1=Blue-Eye Paramyxovirus#Introduction
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|l1=Blue Eye Disease#Introduction
|q2=In what systems are affected by ''Blue eye disease''?
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|q2=What viruses are closely related to it?
|a2= Systems:
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|a2=
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*Mumps virus
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*Simian virus 5
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|l2=Blue Eye Disease#Introduction
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|q3=What are the properties of this virus?
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|a3=
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*mainly spherical but it is polymorphic
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*enveloped - which is covered in surface projections
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*135-148nm by 257-360nm
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*buoyant density in sucrose gradients of 1.21 g/ml
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*six structural proteins and the envelope nucleocapsid expresses hemagglutinin-neuraminidase and fusion and matrix proteins.
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*resistant to actinomycin D and sensitive to chloroform, formalin and beta propiolactone.
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|l3=Blue Eye Disease#Introduction
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|q4=What systems are affected by Blue eye disease?
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|a4=  
 
*Nervous systems
 
*Nervous systems
 
*Reproductive systems
 
*Reproductive systems
 
*Respiratory systems
 
*Respiratory systems
|l2=Blue Eye Disease#Introduction
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|l4=Blue Eye Disease#Introduction
|q3=What ages of pigs are affected by this disease?
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|q5=What are the wild and domestic hosts of this virus?
|a3= All:
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|a5=
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Domestic hosts include:
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*Dogs
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*Cats
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*Pigs
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Wild hosts include:
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*Rabbits
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*Rats
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*Ferral cats and dogs
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*Peccary's
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Clinical signs are only seen in the pig, but antibodies can be detected in rabbits, rats, dogs and cats.
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|l5=Blue Eye Disease#Signalment
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|q6=What ages of pigs are affected by this disease?
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|a6= All:
 
*Piglets
 
*Piglets
 
*Weaners
 
*Weaners
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*Sows
 
*Sows
 
*Boars
 
*Boars
|l3=Blue-Eye Paramyxovirus#Signalment
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|l6=Blue Eye Disease#Signalment
|q4=What clinical signs are generally associated with ''Blue eye disease '' in all ages of pigs?
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|q7=What clinical signs are generally associated with Blue eye disease in all ages of pigs?
|a4=  
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|a7=  
*General signs include anorexia, weight loss, reluctance to move, dehydration, periorbital and conjunctival swelling (chemosis) and purulent/serous ocular discharge and corneal opacity.  
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*Anorexia
 
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*Weight loss
*Neurological signs include tetraparesis, opisthotonus, dysmetria, proprioceptive disorders, tremors, nystagmus mydriasis, blindness, decreased or absent menace response and respiratory signs; tachypnea, dyspnea, and open mouthed breathing.
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*Reluctance to move
|l4=Blue Eye Disease#Clinical Signs
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*Dehydration
|q5=What clinical signs are associated with Sows?
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*Periorbital and conjunctival swelling (chemosis)
|a5=In sows the disease causes infertility, reproductive failures, embryonic mortality and return to oestrus in the first third of gestation and stillbirths, small litters and mummification in late gestation.
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*Purulent/serous ocular discharge
|l5=Blue Eye Disease#Clinical Signs
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*Corneal opacity.  
|q6=What clinical signs are associated with piglets and weaners?
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*Neurological signs (tetraparesis, opisthotonus, dysmetria, proprioceptive disorders, tremors, nystagmus mydriasis, blindness, decreased or absent menace response)
|a6= Piglet and weaners suffer from prostration, hind limb stiffness, generalised weakness, muscle fasciculation’s, retarded growth, depression, excitation, head pressing, circling, hyperaesthesia, abnormal behaviour/aggression and coma.
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*Respiratory signs (tachypnea, dyspnea, and open mouthed breathing)  
 
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In piglets the disease also causes changes in hair coat (dull/rough), ocular erosions, enlarged distended bladder and constipation/reduction in faces or diarrhoea.
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|l6=Blue Eye Disease#Clinical Signs
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|q7=What clinical signs are associated with boars?
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|a7=In the boar it causes male infertility, lack of libido, haemospermia, and orchitis with epidydimitis and swelling of the genitals.
   
|l7=Blue Eye Disease#Clinical Signs
 
|l7=Blue Eye Disease#Clinical Signs
|q8=What causes ''Blue eye disease '' in pigs?
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|q8=What clinical signs are associated with the virus in sows?
|a8=  
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|a8=In the first third of gestation:
|l8=Blue Eye Disease#Introduction
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*Infertility
|q9=What causes ''Blue eye disease '' in pigs?
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*Reproductive failures
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*Embryonic mortality
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*Return to oestrus
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In late gestation:
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*Stillbirths
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*Small litters
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*Mummification
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|l8=Blue Eye Disease#Clinical Signs
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|q9=What clinical signs are associated with the virus in piglets and weaners?
 
|a9=  
 
|a9=  
|l9=Blue Eye Disease#Introduction
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Piglet and weaners:
|q10=What causes ''Blue eye disease '' in pigs?
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*Prostration
|a10=  
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*Hind limb stiffness
|l10=Blue Eye Disease#Introduction
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*Generalised weakness
|q11=What causes ''Blue eye disease '' in pigs?
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*Muscle fasciculation’s
|a11=  
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*Retarded growth
|l11=Blue Eye Disease#Introduction
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*Depression
|q12=What causes ''Blue eye disease '' in pigs?
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*Excitation
|a12=  
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*Head pressing
|l12=Blue Eye Disease#Introduction
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*Circling
|q13=What causes ''Blue eye disease '' in pigs?
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*Hyperaesthesia
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*Abnormal behaviour/aggression
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*Coma
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In piglets:
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*Changes in hair coat (dull/rough)
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*Ocular erosions
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*Enlarged distended bladder
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*Constipation/reduction in faces or diarrhoea
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|l9=Blue Eye Disease#Clinical Signs
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|q10=What clinical signs are associated with boars?
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|a10=
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*Male infertility
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*Lack of libido
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*Haemospermia
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*Orchitis with epidydimitis
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*Swelling of the genitalia
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|l10=Blue Eye Disease#Clinical Signs
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|q11=What is the epidemiology of Blue eye disease?
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|a11=
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*The virus is spread via direct contact, fomites and possibly birds
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*Virus can be found in the axon of neurons
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*Original site of replication is thought to be the nasal mucosa and tonsils
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*It can be found in tissues (lung, liver, spleen, kidney, lymph node, heart and testis)
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*Hematogenous spread is likely
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|l11=Blue Eye Disease#Epidemiology
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|q12=What is the distribution of Blue eye disease in pigs?
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|a12=The disease appears restricted to Central Mexico and its states.
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|l12=Blue Eye Disease#Distribution
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|q13=What is the treatment for Blue eye disease?
 
|a13=  
 
|a13=  
|l13=Blue Eye Disease#Introduction
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*No treatment is available for Blue eye disease
 
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*Supportive medication for respiratory and inflammatory disease should be administered
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*Euthanasia may be necessary for ataxic pigs.
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|l13=Blue Eye Disease#Treatment
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|q14=How is Blue eye disease controlled?
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|a14=
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*The disease is self limiting
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*Closed herds once infected will have sporadic outbreaks of the disease
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*There is no approved vaccine for the control of blue eye disease
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*Elimination can be achieved by:
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**Closed herds
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**All-in/all-out systems
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**Good washing and disinfecting protocols
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|l14=Blue Eye Disease#Control
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|q15=Is Blue eye disease considered a zoonosis?
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|a15=
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No
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|l15=Blue Eye Disease#Introduction
 
</FlashCard>
 
</FlashCard>
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==Further links==
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[[Actinobacillus suis| Actinobacillus suis'']]
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[[Blue-Eye Paramyxovirus Flashcards| ''Blue-Eye Paramyxovirus'' Flashcards]]
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[[Blue-Eye Paramyxovirus| ''Blue-Eye Paramyxovirus'']]
        −
[[Category: Pig Flashcards]]
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[[Category:Pig Flashcards]]
 
[[Category:CABI Flashcards]]
 
[[Category:CABI Flashcards]]
[[Category: To Do - Jaimie Meagor]]
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[[Category:Reproductive Diseases Flashcards]]
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[[Category:Respiratory Diseases Flashcards]]
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[[Category:Neurological Diseases Flashcards]]
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