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Materno-fetal Immunity Flashcards (view source)

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===Passive Transfer and Failure of Passive Transfer (FPT)===
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|backcolour = FFE4E1
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<FlashCard questions="10">
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|linkpage =Materno-fetal immunity - WikiBlood
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|q1=How can antibodies be transferred between individuals?
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|linktext =MATERNO-FETAL IMMUNITY
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|a1=
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|sublink1 =Flash Cards - WikiBlood
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*Colostrum
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|subtext1 =WIKIBLOOD FLASHCARDS
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*Crossing of the placenta
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|pagetype =Blood
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*Milk
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}}
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*Vaccination
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*Plasma transfusions
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==<font color="purple">Complement Fixation Pathways</font>==
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|l1=Materno-Fetal Immunity - Introduction
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{| border="3" cellpadding="8"
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|q2=Why do neonates require maternal antibodies?
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!width="400"|'''Question'''
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|a2=
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!width="400"|'''Answer'''
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*Immunocompromised at birth due to a poorly developed immune system
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!width="150"|'''Article'''
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*Mucosal surfaces are particularly vunerable
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|-
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*Colostral and milk antibodies protect neonates from infection
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|<big>'''What are the names of the different pathways of the complement cascade?'''
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|l2=Materno-Fetal Immunity - Introduction
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||<font color="white"> <big>
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|q3=In which animals is there no passive transfer of IgG antibodies across the placenta?
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*'''''Classical'''''
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|a3=
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*'''''Alternative'''''
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*Ruminants
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*'''''Mannose-binding Lectin'''''
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*Horses
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||[[Materno-fetal immunity - WikiBlood|<span title="Answer article">Link to Answer Article</span>]]
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*Pigs
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|}
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|l3=Materno-Fetal Immunity - Introduction
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<br>
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|q4=What type of placenta do dogs and cats have?
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<br>
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|a4=Endotheliochorial
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<big><center>[[Materno-fetal immunity - WikiBlood|'''BACK TO MATERNO-FETAL IMMUNITY''']]</center></big>
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|l4=Materno-Fetal Immunity - Introduction
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<big><center>[[Flash Cards - WikiBlood|'''BACK TO WIKIBLOOD FLASHCARDS''']]</center></big>
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|q5=What does colostrum contain?
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|a5=
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*Immune factors
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*Growth factors
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*Vitamins
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*Minerals
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|l5=Materno-Fetal Immunity - Introduction
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|q6=Which immunoglobulins are present in colostrum?
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|a6=
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*IgG in the largest amount
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*IgA
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*IgM
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|l6=Materno-Fetal Immunity - Introduction
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|q7=True or False: IgA is most abundent in ruminant milk
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|a7=
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*False
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*IgG is most abundent in ruminant milk
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*IgA is most abundent in non-ruminant milk
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|l7=Materno-Fetal Immunity - Introduction
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|q8=When does inadequate absorption of immunoglobulins occur in the neonate?
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|a8=
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*The neonate does not recieve colostrum
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*The neonate does not recieve enough colostrum
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*The neonate does not absorb enough colostrum
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*The quality of the colostrum was inadequate
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|l8=Failure of Passive Transfer
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|q9=What does colostrum quality depend upon?
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|a9=
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*Breed
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*Nutrition
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*Season
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*Stress
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*Immunostatus of the dam
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*Milk yield
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*Pre-milking
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*Parity
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*Dripping from the teats
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|l9=Failure of Passive Transfer
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|q10=What does the quantity of colostrum depend upon?
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|a10=
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*Amount the neonate suckles
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*Premature births
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|l10=Failure of Passive Transfer
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</FlashCard>
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===Testing Colostrum Quality===
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<FlashCard questions="9">
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|q1=True or False: Colostrum quality can not be determined by appearance
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|a1=True
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|l1=Colostrum Quality Testing
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|q2=How can colostrum be stored without reducing its immunological potential?
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|a2=
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*Freezing immediately will make the colostrum last for a year
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*Refridgerating immediately will make the colostrum last for 5-7 days
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|l2=Colostrum Quality Testing
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|q3=How can the immune status of colostrum be tested?
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|a3=
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*By a colostrometer
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*Through using the Zinc Sulfate Turbidity (ZST) test
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*Total serum protein can be calculated
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|l3=Colostrum Quality Testing
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|q4=Which immunoglobulin levels does a colostrometer measure?
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|a4=IgG
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|l4=Colostrum Quality Testing
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|q5=Why must colostrum be tested by a colostrometer at room temperature (20°C)?
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|a5=
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*Above 20°C levels of IgG will be underestimated
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*Below 20°C levels of IgG will be overestimated
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|l5=Colostrum Quality Testing
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|q6=What levels of ZST units would indicate a healthy amount of passive transfer in calves?
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|a6=Above 30 ZST units
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|l6=Colostrum Quality Testing
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|q7=What levels of serum immunoglobulin would indicate a healthy amount of passive transfer in foals?
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|a7=Above 800 mg/dl
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|l7=Colostrum Quality Testing
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|q8=What is total serum protein levels measured by and at which ages should neonates be tested?
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|a8=
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*A refractometer
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*2-8 days old
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|l8=Colostrum Quality Testing
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|q9=What levels of serum protein indicate the neonate is healthy and does not require further colostrum?
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|a9=Above 4.5 mg/dl
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|l9=Colostrum Quality Testing
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</FlashCard>
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===Neonatal Isoerythrolysis (NI)===
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<FlashCard questions="3">
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|q1=When does alloimmune haemalytic anaemia occur?
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|a1=
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*When a neonate inherits the sires blood type and drinks colostrum from the dam
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*As the colostrum contains antibodies against the sire and thus the neonates red blood cells
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|l1=Neonatal Isoerythrolysis
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|q2=When does Neonatal Isoerythrolysis occur?
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|a2=
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*First pregnancy from a stallion with incompatible blood type to the mare
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*Subsequent pregnancy from the same stallion or same blood group as previously exposed to
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|l2=Neonatal Isoerythrolysis
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|q3=True or False: Neonatal Isoerythrolysis always occurs in mules
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|a3=True
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|l3=Neonatal Isoerythrolysis
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</FlashCard>
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<br><br>
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{{Jim Bee 2007}}
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[[Category:Materno-Fetal Immunity|Z]]
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[[Category:Immunology Flashcards]]
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