Changes

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Along with the actions of the fragments mentioned above, Ca fragments C3a, C4a and C5a, and Cb fragment C2b also form a chemotactic response. This brings [[Neutrophils|neutrophils]] to the area of complement activation through the process of [[Neutrophils|extravasation]] through the increase in cell adhesion molecules on the endothelium and an increase in vascular permeability; and chemotaxis which is the direct cellular movement. The fragments can also cause [[Mast Cells|mast cell]] and [[Basophils|basophil]] degranulation. These therefore induce '''acute inflammation'''.

Along with the actions of the fragments mentioned above, Ca fragments C3a, C4a and C5a, and Cb fragment C2b also form a chemotactic response. This brings [[Neutrophils|neutrophils]] to the area of complement activation through the process of [[Neutrophils|extravasation]] through the increase in cell adhesion molecules on the endothelium and an increase in vascular permeability; and chemotaxis which is the direct cellular movement. The fragments can also cause [[Mast Cells|mast cell]] and [[Basophils|basophil]] degranulation. These therefore induce '''acute inflammation'''.

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