Where there are breaks in the skin that are open to the outside environment the body has an armoury of biochemical barrieres that can stop infection. These are:
* '''Lactic and fatty acids''' in sweat and sebaceous secretions are directly bacteriocidal
* '''Lactic and fatty acids''' in sweat and sebaceous secretions are directly bacteriocidal
* '''Enzymes''' e.g. lysozyme in saliva, sweat & tears and Gastric acid denature microorganisms
* '''Enzymes''' e.g. lysozyme in saliva, sweat & tears and Gastric acid denature microorganisms