|
|
| (11 intermediate revisions by 2 users not shown) |
| Line 1: |
Line 1: |
| − | *Causes [[Glanders|glanders]], a contagious disease of ''Equidae''
| + | #redirect[[Glanders]] |
| − | *Nodules and ulcers in respiratory tract and on skin
| |
| − | *Largely eradicated but sporadic cases in Middle East, India, China
| |
| − | *Pathogenesis:
| |
| − | **Transmited by ingestion of food/water contaminated by nasal discharge of infected ''Equidae''; occasionally via inhalation or skin wounds
| |
| − | **Organism invades nasopharyngeal mucosa and spreads to other tissues via lymphatics
| |
| − | **Presence of ''B. mallei'' in host causes hypersensitivity reaction
| |
| − | *Clinical infections:
| |
| − | **Acute septicaemic form with fever, mucopurulent nasal discharge and respiratory signs; death within weeks
| |
| − | **Chronic disease more common:
| |
| − | ***Nasal form: [[Nasal Cavity Inflammatory - Pathology#Infectious causes of rhinitis|rhinitis]]; ulcerative nodules develop on mucosa of nasal septum and lower part of turbinates; purulent blood-stained nasal discharge; regional lymphadenitis
| |
| − | ***Respiratory form: respiratory distress; granulomatous lesions throughout lungs
| |
| − | ***Cutaneous form (farcy): lymphangitis; nodules along lymphatic vesselsof limbs; ulcers develop and discharge pus
| |
| − | ***May die after several months or recover and shed organisms from respiratory tract or skin
| |
| − | **Carnivores may contract disease by eating infected carcasses
| |
| − | *Diagnosis:
| |
| − | **Specimens include discharges from lesions and blood for serology
| |
| − | **Grows on media containing 1% glycerol; most strains are non-lactose fermenters on MacConkey agar
| |
| − | **Complement fixation and agglutination
| |
| − | **Serology
| |
| − | **Mallein test: mallein injected intradermally below lower eyelid; local swelling and discharge indicates positive reation
| |
| − | *Treatment/control:
| |
| − | **Test and slaughter policy where disease exotic
| |
| − | **Disinfection of contaminated areas using formalin or an iodophor
| |
| | | | |
| − | [[Category:Pseudomonas_and_Burkholderia_species]][[Category:Horse]] | + | |
| − | [[Category:To_Do_-_Bacteria]]
| + | [[Category:Pseudomonas_and_Burkholderia_species|B]] |