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| + | ==Introduction== |
| + | Eosinopaenia refers to a reduction in the normal number of circulating blood [[Eosinophil|eosinophils]]. It ocurs most commonly as part of a [[Stress Leucogram|stress leucocgram]] and in other situations that result in an increase in the circulating concentration of glucocorticoids: |
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− | * Eosinopenia is a reduction in the number of eosinophils in the blood. | + | *'''Stress leucogram''', with which [[Neutrophilia|neutrophilia]], [[Monocytosis|monocytosis]] and [[Lymphopenia|lymphopaenia]] would also be expected. |
| + | *'''[[Hyperadrenocorticism]]''' (Cushing's disease) results in a similar pattern due to an increase in endogenous glucocorticoids. |
| + | *'''Iatrogenic hyperadrenocorticism''' caused by the administration of corticosteroids, even with the use of topical otic or ophthalmic preparations. |
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− | * Occurs as part of the response to corticosteroids;.
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− | ** Thought to be associated with the depressive effect of corticosteroids on lymphocytes.
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− | *** Secretions of these lymphocytes are thought to stimulate eosinophil production.
| + | Corticosteroids are thought to exert a depressive effect on lymphocytes which usually stimulate eosinophil production. |
− | [[Category:Inflammation]][[Category:To Do - Blood]] | + | |
| + | {{Learning |
| + | |literature search = [http://www.cabdirect.org/search.html?q=title:(Eosinopenia)+OR+title:(Eosinopaenia)&fq=sc:%22ve%22 Eosinopenia specific publications] |
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| + | [http://www.cabdirect.org/search.html?rowId=1&options1=AND&q1=Eosinopenia&occuring1=ab&rowId=2&options2=OR&q2=Eosinopaenia&occuring2=ab&rowId=3&options3=AND&q3=&occuring3=freetext&x=33&y=11&publishedstart=yyyy&publishedend=yyyy&calendarInput=yyyy-mm-dd&la=any&it=any&show=all Eosinopaenia mentioned in abstract of publications] |
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| + | [[Category:Haematology Changes]][[Category:Expert Review]] |