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==Introduction==
==Description==
Eosinopaenia refers to a reduction in the normal number of circulating blood [[Eosinophil|eosinophils]]. It ocurs most commonly as part of a [[Stress Leucogram|stress leucocgram]] and in other situations that result in an increase in the circulating concentration of glucocorticoids:
Eosinopaenia refers to a reduction in the normal number of circulating blood [[Eosinophil|eosinophils]]. It ocurs most commonly as part of a stress leucocgram and in other situations that result in an increase in the circulating concentration of glucocorticoids:
*'''Stress leucogram''', with which [[Neutrophilia|neutrophilia]], [[Monocytosis|monocytosis]] and [[Lymphopenia|lymphopaenia]] would also be expected.
*'''Stress leucogram''', with which [[Neutrophilia|neutrophilia]], [[Monocytosis|monocytosis]] and [[Lymphopenia|lymphopaenia]] would also be expected.
*'''Hyperadrenocorticism''' (Cushing's disease) results in a similar pattern due to an increase in endogenous glucocorticoids.
*'''[[Hyperadrenocorticism]]''' (Cushing's disease) results in a similar pattern due to an increase in endogenous glucocorticoids.
*'''Iatrogenic hyperadrenocorticism''' caused by the administration of corticosteroids, even with the use of topical otic or ophthalmic preparations.
*'''Iatrogenic hyperadrenocorticism''' caused by the administration of corticosteroids, even with the use of topical otic or ophthalmic preparations.
[[Category:Haematology Changes]][[Category:To Do - James]]
Corticosteroids are thought to exert a depressive effect on lymphocytes which usually stimulate eosinophil production.
{{Learning
|literature search = [http://www.cabdirect.org/search.html?q=title:(Eosinopenia)+OR+title:(Eosinopaenia)&fq=sc:%22ve%22 Eosinopenia specific publications]
[http://www.cabdirect.org/search.html?rowId=1&options1=AND&q1=Eosinopenia&occuring1=ab&rowId=2&options2=OR&q2=Eosinopaenia&occuring2=ab&rowId=3&options3=AND&q3=&occuring3=freetext&x=33&y=11&publishedstart=yyyy&publishedend=yyyy&calendarInput=yyyy-mm-dd&la=any&it=any&show=all Eosinopaenia mentioned in abstract of publications]
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[[Category:Haematology Changes]][[Category:Expert Review]]