Changes

Also Known As: '''''IBR — Cytomegalic Inclusion Disease'''''

Also Known As: '''''IBR — Cytomegalic Inclusion Disease'''''

PCMV may pose a risk to humans through '''transplanted organs''' and this is currently being researched. It is not currently considered a zoonosis due to its host range being highly restricted to only the pig.

PCMV may pose a risk to humans through '''transplanted organs''' and this is currently being researched. It is not currently considered a zoonosis due to its host range being highly restricted to only the pig.

==Epidemiology==

 

==Distribution==

'''Global'''. No country has established freedom from or eradication of disease. Prevalence of infected herds and infected pigs within a herd is very high albeit with a low incidence of clinical disease.

'''Global'''. No country has established freedom from or eradication of disease. Prevalence of infected herds and infected pigs within a herd is very high albeit with a low incidence of clinical disease.

'''Antigen''' can be detected serologically by [[FAT|'''fluorescent antibody test (FAT)]].'''

'''Antigen''' can be detected serologically by [[FAT|'''fluorescent antibody test (FAT)]].'''

'''Antibody''' can be detected by '''Indirect Fluorescent Antibody Test (IFAT).'''

 

'''Antibody''' can be detected by '''Indirect Fluorescent Antibody Test (IFAT) and [[ELISA testing|ELISA]].'''

'''PCR''' tests for PCMV have now also been developed and are very sensitive.

'''PCR''' tests for PCMV have now also been developed and are very sensitive.

On '''post-mortem''', petechiation of the heart, kidneys, intestine, lungs, lymph nodes and meninges is seen in neonatal and foetal pigs. Pulmonary congestion is marked and the bronchial and mediastinal lymph nodes are dramatically enlarged. Ventral aspects of lung lobes are often '''discoloured purple'''. The nasal mucosa is congested with a mucoid exudates.

On '''post-mortem''', petechiation of the heart, kidneys, intestine, lungs, lymph nodes and meninges is seen in neonatal and foetal pigs. Pulmonary congestion is marked and the bronchial and mediastinal lymph nodes are dramatically enlarged. Ventral aspects of lung lobes are often '''discoloured purple'''. The nasal mucosa is congested with a mucoid exudate.

Histologically, large '''basophilic intranuclear inclusion bodies are present in the mucosal epithelial cells''' of the turbinates, salivary glands and kidney tissues.  

Histologically, large '''basophilic intranuclear inclusion bodies are present in the mucosal epithelial cells''' of the turbinates, salivary glands and kidney tissues.  

Electron microscopy can also be used for the same purpose.  

Electron microscopy can also be used for the same purpose.  

==Treatment==

==Treatment==

==References==

==References==

<references/>

<references/>

Animal Health & Production Compendium, '''Inclusion Body Rhinitis datasheet''', accessed 16/06/2011 @ http://www.cabi.org/ahpc/

|datasheet = [http://www.cabi.org/ahpc/?compid=3&dsid=79245&loadmodule=datasheet&page=2144&site=160 inclusion body rhinitis] and [http://www.cabi.org/ahpc/Default.aspx?site=160&page=2144&LoadModule=datasheet&CompID=3&dsID=62346 suid herpesvirus 2]

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[[Category:Herpesviridae]]

[[Category:CABI Expert Review Completed]][[Category:CABI AHPC Pages]]

[[Category:Pig Viruses]]

[[Category:Pig Viruses]]

[[Category:Respiratory Diseases - Pig]]

[[Category:Respiratory Diseases - Pig]]

[[Category:Reproductive Diseases - Pig]]

[[Category:Reproductive Diseases - Pig]]