Changes

==Introduction==

==Introduction==

* Haemorrhage is the escape of blood from within the cardiovascular system.

* Haemorrhage is the escape of blood from within the cardiovascular system.

** Neoplastic disease.

** Neoplastic disease.

* "Haemorrhagic diathesis" describes a predisposition to bleeding, either spontaneous or associated with trifling mechanical damage.   

* "Haemorrhagic diathesis" describes a predisposition to bleeding, either spontaneous or associated with trifling mechanical damage.   

** Often manifests as [[Haemorrhage - Pathology#Purpura|purpuric disease]].  

** Often manifests as [[Haemorrhage#Purpura|purpuric disease]].  

** Haemorrhagic diatheses and [[Haemorrhage - Pathology#Purpura|purpura]] may be a feature of a number of diseases of different aetiology (poisoning, septicaemia or neoplastic disease).

** Haemorrhagic diatheses and [[Haemorrhage#Purpura|purpura]] may be a feature of a number of diseases of different aetiology (poisoning, septicaemia or neoplastic disease).

==Types of Haemorrhage==

==Types of Haemorrhage==

* Two main types of haemorrhage are recognised and are considered in more detail below:

* Two main types of haemorrhage are recognised and are considered in more detail below:

** '''[[Haemorrhage - Pathology#Haemorrhage by Rhexis|Rhexis]]'''

** '''[[Haemorrhage#Haemorrhage by Rhexis|Rhexis]]'''

*** Actual physical rupture of a vessel wall

*** Actual physical rupture of a vessel wall

** '''[[Haemorrhage - Pathology#Haemorrhage by Diapedesis|Diapedesis]]'''  

** '''[[Haemorrhage#Haemorrhage by Diapedesis|Diapedesis]]'''  

*** The escape of blood from vessels.

*** The escape of blood from vessels.

*** It may be difficult to detect a disruption to the vessel wall.

*** It may be difficult to detect a disruption to the vessel wall.

===Purpura===

===Purpura===

* Purpura is a clinical syndrome.  

* [[Purpura haemorrhagica|Purpura]] is a clinical syndrome.  

* Multiple small spontaneous haemorrhages develop in tissues (e.g. skin, mucosae, serosal surfaces and joints).

* Multiple small spontaneous haemorrhages develop in tissues (e.g. skin, mucosae, serosal surfaces and joints).

* A mixture of petechiae and ecchymoses.

* A mixture of petechiae and ecchymoses.

** Loss of 30-40 per cent in a few minutes is often fatal.

** Loss of 30-40 per cent in a few minutes is often fatal.

** Loss of over 50% over a 24 period may be tolerated in the dog.

** Loss of over 50% over a 24 period may be tolerated in the dog.