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− | {{review}} | + | {{frontpage |
| + | |pagetitle =Teeth - Pathology |
| + | |pagebody = |
| + | |contenttitle =Content |
| + | |contentbody =<big><b> |
| + | <br><br> |
| + | <categorytree mode=pages>Teeth - Pathology</categorytree> |
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− | ==Introduction== | + | </b></big> |
| + | |logo =path-logo.png |
| + | }} |
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− | See [[Oral Cavity - Teeth & Gingiva - Anatomy & Physiology|anatomy and physiology of the teeth]]
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− | ==Functional Anatomy==
| + | [[File:Toothinfection.gif|200px]] |
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− | *The [[Cavity & Gingiva - Pathology|gingival crevice]] is an important site for disease processes in mouth to begin.
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− | *In ruminants and rodents [[Oral Cavity - Teeth & Gingiva - Anatomy & Physiology|teeth]] may fail to oppose properly or to allow side to side movement of jaws. This produces uneven wear (especially in horse). Sharp edges are produced on the outside of the [[Oral Cavity - Teeth & Gingiva - Anatomy & Physiology|teeth]] in the upper jaw and inside of the [[Oral Cavity - Teeth & Gingiva - Anatomy & Physiology|teeth]] in the lower jaw, which causes painful feeding and inanition (not eating).
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− | **Approximately 75% of wasting horses have dental abnormalities.
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− | *This is not a problem in carnivores as do they not use [[Oral Cavity - Teeth & Gingiva - Anatomy & Physiology|teeth]] for [[Mastication|mastication]].
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− | *If a [[Oral Cavity - Teeth & Gingiva - Anatomy & Physiology|teeth]] is lost the opposing [[Oral Cavity - Teeth & Gingiva - Anatomy & Physiology|teeth]] may become very long and stop mouth closing properly.
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− | **Seen mostly in rodents - [[Oral Cavity - Teeth & Gingiva - Anatomy & Physiology|teeth]] may even penetrate through [[Lips - Anatomy & Physiology|lip]].
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− | ==Defence Mechanisms==
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− | ==Developmental Pathology==
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− | ===[[Erythropoietic Porphyra]].===
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− | ===[[Photosensitisation]]===
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− | ===[[Abnormal Wear of Teeth]]===
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− | ===[[Abnormal Numbers of Teeth]]===
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− | ==Infection of teeth==
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− | ===[[Alveolar Periostitis]]===
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− | ==Granulomatous and pyogranulomatous Inflammation==
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− | ===[[Mandibular Osteomyelitis]]===
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− | ===[[Odontoclastic resorptive lesions]]===
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− | ==Eosinophilic Inflammation==
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− | ==Necrotizing Inflammation==
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− | ==Lymphocytic and plasmacytic Inflammation==
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− | ==Proliferative Pathology==
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− | ===Hyperplastic===
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− | ====Focal fibrous hyperplasia<ref name="epulides1"> </ref>====
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− | *44% of cases.
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− | *Dense collagenous tissue, with ulceration/superficial inflammation
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− | *Dystrophic calcificaition within the fibrous connective tissue stroma (often highly cellular, with 'young stellate fibroblasts'
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− | *No odontogenic epithelium seen.
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− | *Occasional strands of surface epithelium growing down into the stroma.
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− | *Most of these were previously diagnosed as fibromatous or ossifying epulides.
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− | ===Neoplastic===
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− | ====Peripheral odontogenic fibroma<ref name="epulides1">J Comp. Path. 1992 (106), 169-182 The Histological Nature of Epulides in Dogs F. J. M. Verstraete*, A. J. Ligthelmf and A. WeberT. ... review of 154 oral 'epulis' from dogs reviewed with the current (at the time) human literature.</ref>====
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− | [[Image:epulis.gif|right|thumb|125px|<small><center>Canine Epulis (Courtesy of Alun Williams (RVC))</center></small>]]
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− | *aka: Fibromatous epulis of periodontal ligament origin
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− | *17% of cases.
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− | *Proliferation of fibrous tissue with variety of osteoid, [[Cementum - Anatomy & Physiology|cementum]] or [[Dentine - Anatomy & Physiology|dentine]]-like material.
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− | *Isolated strands or islands of odontogenic epithelium always present (ie: suggesting induction of connective tissue by the epithelial cells).
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− | *The stroma contains neoplastic fibroblasts, with varying cellularity.
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− | *The overlying epitheluim is normal.
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− | ====Peripheral ameloblastoma<ref name="epulides1"> </ref>====
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− | [[Image:ameloblastoma.gif|right|thumb|125px|<small><center>Ameloblastoma (Courtesy of Alun Williams (RVC))</center></small>]]
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− | *aka: basal cell carcinoma, acanthomatous ameloblastoma, acanthomatous epulis
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− | *18% of cases.
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− | *Islands and sheets of mature odontogenic epithelium within a collagenous fibrous connective tissue stroma of low/moderate cellularity.
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− | *Each of the islands bounded by a row of tall columnnar cells.
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− | *These palisading cells exhibit polarisation away from the basement membrane and had cytoplasmic vacuolation.
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− | *Central cells had a basaloid appearance.
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− | *Often infiiltrating into the underlying bone.
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− | *Synonymous with basal cell carcinoma.
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− | ====Central ameloblastoma<ref name="epulides1"> </ref>====
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− | *Different from peripheral ameloblastoma - cystic changes and follicular arrangement of ameloblasts and stellate reticulum cells, resembling the basic structure of the [[Tooth Anatomy - Anatomy & Physiology|enamel organ]].
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− | ==Degenerative Pathology==
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− | ===Odontodystrophy===
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− | *Damage to [[Ameloblasts - Anatomy & Physiology|ameloblasts]] (which form [[Enamel - Anatomy & Physiology|enamel]]) in utero upsets permanent incisor formation.
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− | *[[Enamel - Anatomy & Physiology|Enamel]] is marked by pits, lines etc.
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− | ====In ruminants:====
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− | *Damage to [[Enamel - Anatomy & Physiology|enamel]] formation most often caused by fluoride poisoning.
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− | *Seen in cattle grazing on pasture contaminated by cement works effluent.
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− | *Chalky mottling and yellow brown pitting of [[Oral Cavity - Teeth & Gingiva - Anatomy & Physiology|tooth]].
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− | ====In canines:====
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− | [[Image:enamal-hypoplasia.gif|right|thumb|125px|<small>Enamal Hypoplasia Following a CDV infection (Courtesy of Alun Williams (RVC))<center></center></small>]]
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− | Very severe systemic disease early in life / or in utero may result in severe discoloration or pitting of [[Oral Cavity - Teeth & Gingiva - Anatomy & Physiology|teeth]] due to effect on [[Enamel - Anatomy & Physiology|enamel]] formation. (e.g. [[Paramyxoviridae#Canine Distemper Virus (CDV)|distemper in dog]])
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− | ==Metabolic Pathology==
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− | ==Nutritiona Pathology==
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− | ==Traumatic Pathology==
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− | ==Vascular Pathology==
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− | ==References==
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− | <small>
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− | With thanks to Andrew Jefferies (Cambridge) and Alun Williams (RVC) for providing access to their lecture materials
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− | <references/>
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− | </small>
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− | ==Learning Tools==
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− | [[Alimentary Flashcards - Pathology#Teeth Flashcards|Teeth Flashcards]]
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| [[Category:Oral_Cavity_and_Gingiva_-_Pathology]] | | [[Category:Oral_Cavity_and_Gingiva_-_Pathology]] |