Difference between revisions of "Sexual Differentiation - Anatomy & Physiology"
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+ | == Genetic Sex == | ||
+ | * Established at the time of '''fertilisation'''. | ||
+ | * The foetus receives its genetic endowment in two equal portions from the male gamete ('''Spermatozoon''') and female gamete ('''Oocyte'''). | ||
+ | * The X sex chromosome is larger than the Y sex chromosome. | ||
+ | * '''Females''' have XX chromosomes. All oocytes contain one X chromosome, they are the '''homogametic''' sex. | ||
+ | * '''Males''' have XY chromosomes. Spermatozoa form two distinct populations, one containing X chromosomes and one containing Y chromosomes. They are the '''heterogametic''' sex. | ||
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+ | * The '''Y''' chromosome is required to '''initiate male development'''. | ||
+ | * In absence of the Y chromosome, female gonads (Ovaries) will develop. | ||
+ | * The prime male determining gene is '''SRY''' (sex determining region of the Y chromosome). SRY is a very small piece of DNA that acts as a molecular switch to regulate structural genes and autosomal chromosomes | ||
+ | * The presence of SRY alone is sufficient to ensure development of male gonads (Testes). | ||
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+ | == Internal Genetalia == | ||
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+ | == External Genetalia == | ||
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− | + | ::[[Fertilisation, Implantation and Early Embryonic Development -Sexual Differentiation - Anatomy & Physiology|Turner's Syndrome]] | |
− | + | ::[[Fertilisation, Implantation and Early Embryonic Development -Sexual Differentiation - Anatomy & Physiology|Kleinfelter's Syndrome]] | |
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+ | ::[[Fertilisation, Implantation and Early Embryonic Development -Sexual Differentiation - Anatomy & Physiology|Testicular Feminisation]] | ||
+ | ::[[Fertilisation, Implantation and Early Embryonic Development -Sexual Differentiation - Anatomy & Physiology|Adrenogenital Syndrome]] | ||
− | [[ | + | ::[[Fertilisation, Implantation and Early Embryonic Development -Sexual Differentiation - Anatomy & Physiology|Bovine Freemartinism]] |
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Revision as of 09:20, 3 July 2008
Genetic Sex
- Established at the time of fertilisation.
- The foetus receives its genetic endowment in two equal portions from the male gamete (Spermatozoon) and female gamete (Oocyte).
- The X sex chromosome is larger than the Y sex chromosome.
- Females have XX chromosomes. All oocytes contain one X chromosome, they are the homogametic sex.
- Males have XY chromosomes. Spermatozoa form two distinct populations, one containing X chromosomes and one containing Y chromosomes. They are the heterogametic sex.
- The Y chromosome is required to initiate male development.
- In absence of the Y chromosome, female gonads (Ovaries) will develop.
- The prime male determining gene is SRY (sex determining region of the Y chromosome). SRY is a very small piece of DNA that acts as a molecular switch to regulate structural genes and autosomal chromosomes
- The presence of SRY alone is sufficient to ensure development of male gonads (Testes).