Difference between revisions of "Liver Endocrine Function - Anatomy & Physiology"

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<big><center>[[Endocrine System - Anatomy & Physiology|'''BACK TO ENDOCRINE SYSTEM ANATOMY & PHYSIOLOGY''']]</center></big>
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The [[Liver - Anatomy & Physiology|liver]] produces some very important hormones:
 
The [[Liver - Anatomy & Physiology|liver]] produces some very important hormones:
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{| border="1" cellpadding="5" cellspacing="0"
 
{| border="1" cellpadding="5" cellspacing="0"
|+ ''Liver hormones''
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|+ ''Liver''
 
!Hormone
 
!Hormone
 
!Regulation and Production
 
!Regulation and Production
 
!Action
 
!Action
 
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|<font color=Purple>Insulin-Like Growth Factor 1 (IGF-1)</font>
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|<font color=Purple>Leptin</font>
|[[Pituitary Growth Hormone - Anatomy & Physiology|Growth Hormone]] released from the pituitary gland binds to receptors on liver cells which causes them to synthesise and secrete IGF-1.
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|Leptin is produced when the body has had adequate to eat.
|IGF-1 has insulin-like effects as it can bind to the Insulin Receptor, and is also the stimulus for growth in the body. Almost all cell types respond to IGF-1.
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|Sends a signal to the ''appetite centre'' of the [[Endocrine System - Hypothalamus - Anatomy & Physiology|Hypothalamus]] indicating satiety. Leptin also seems to be a significant regulator of reproductive function, as animals with low body mass, and thus low leptin levels fail to cycle.
 
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|<font color=Purple>Angiotensinogen</font>
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|<font color=Purple>Resistin</font>
|Angiotensinogen is the precursor to angiotensin 1, and is part of the [[Renin Angiotensin Aldosterone System|Renin-Angiotensin-Aldosterone system]].
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| -  
|Is converted to Angiotensin by [[Kidney Endocrine Function - Anatomy & Physiology|renin]] which in turn is converted to other substrates which act to raise blood pressure during hypotension.
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|Participates in the [[General Pathology - Basic Aspects of the Immune Response|immune response.]] It may have some role in obesity and Type II Diabetes mellitus.
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|<font color=Purple> [[Thrombopoiesis#Thrombopoietin|Thrombopoietin]]</font>
 
|A [[Negative Feedback - Anatomy & Physiology|negative feedback]] system operates to maintain this hormone at an appropriate level.
 
|Causes bone marrow precursor cells to develop into [[Thrombopoiesis#Megakaryocyte|Megakaryocytes]], platelet precursors.
 
 
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[[Category:Endocrine System - Anatomy & Physiology]][[Category:Liver and Gall Bladder - Anatomy & Physiology]]
 

Revision as of 12:33, 3 July 2008

BACK TO ENDOCRINE SYSTEM ANATOMY & PHYSIOLOGY


The liver produces some very important hormones:


Liver
Hormone Regulation and Production Action
Leptin Leptin is produced when the body has had adequate to eat. Sends a signal to the appetite centre of the Hypothalamus indicating satiety. Leptin also seems to be a significant regulator of reproductive function, as animals with low body mass, and thus low leptin levels fail to cycle.
Resistin - Participates in the immune response. It may have some role in obesity and Type II Diabetes mellitus.