| − | There are no published reports of biotin toxicity in dogs and cats<ref name="NRC"/>; excess intake is freely filtered through the renal tubules. | + | There are no published reports of biotin toxicity in dogs and cats<ref name="NRC"/>; excess intake is [[:Category:Urine Production|freely filtered through the renal tubules]]. |
| − | High concentrations of naturally occurring biotin are found in meats, dairy products, grains, and pulses (e.g., legumes). Because endogenous microbial synthesis is normally adequate, a dietary supply of biotin is not required. However supplementation may be necessary in situations where intestinal microbial synthesis is compromised, such as long term administration of anti-bacterial agents. | + | High concentrations of naturally occurring biotin are found in meats, dairy products, grains, and pulses (e.g. legumes). Because endogenous microbial synthesis is normally adequate, a dietary supply of biotin is not required. However supplementation may be necessary in situations where intestinal microbial synthesis is compromised, such as long term administration of [[Antibiotics|anti-bacterial agents]]. |