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=Introduction=
{{frontpage
Asfarviridae receives it's name from [[African Swine Fever|'''A'''frican '''S'''wine '''F'''ever virus]], which is derived from any of this family of viruses. ASF is a serious exotic virus that should not be confused with [[Classical Swine Fever]].
|pagetitle =Asfarviridae
|pagebody = Asfarviridae contains asfivirus, which is the virus of African Swine Fever. This is a serious exotic virus that should not be confused with [[Classical Swine Fever]].
|contenttitle =Content
|contentbody =<big><b>
=Morphology=
<categorytree mode=pages>Asfarviridae</categorytree>
|logo =ASF logo.jpg
}}
==Morphology==
*Large, enveloped, icosahedral, '''cytoplasmic''' DNA virus
*Large, enveloped, icosahedral, '''cytoplasmic''' DNA virus
=Virulence and Pathogenesis=
==Virulence and Pathogenesis==
*Infects either '''upper respiratory tract''' or '''skin''' via '''ticks'''
*Infects either '''upper respiratory tract''' or '''skin''' via '''ticks'''
*Enters bloodstream in [[Monocytes - WikiBlood|monocytes]]
*Enters bloodstream in [[Monocytes|monocytes]]
*Reaches viscera and bone marrow within days
*Reaches viscera and bone marrow within days
*Induces a '''clotting defect''' and '''hemolysis''' in red blood cells
*Induces a '''clotting defect''' and '''hemolysis''' in red blood cells
**Antigen-stimulated B-cells undergo apoptosis rather than producing antibody
**Antigen-stimulated B-cells undergo apoptosis rather than producing antibody
*General cell signal transduction is blocked, decreasing non-specific immunity
*General cell signal transduction is blocked, decreasing non-specific immunity
[[Category:Viruses]]
[[Category:Viral Organisms]]
[[Category:To_Do_-_Clinical/Viruses]]