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{{frontpage
 
{{frontpage
 
|pagetitle =Asfarviridae
 
|pagetitle =Asfarviridae
|pagebody = Asfarviridae receives it's name from [[African Swine Fever|'''A'''frican '''S'''wine '''F'''ever virus]], which is derived from any of this family of virusesASF is a serious exotic virus that should not be confused with [[Classical Swine Fever]].
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|pagebody = Asfarviridae contains asfivirus, which is the virus of African Swine FeverThis is a serious exotic virus that should not be confused with [[Classical Swine Fever]].
 
|contenttitle =Content
 
|contenttitle =Content
 
|contentbody =<big><b>
 
|contentbody =<big><b>
    
<categorytree mode=pages>Asfarviridae</categorytree>
 
<categorytree mode=pages>Asfarviridae</categorytree>
|logo =
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|logo =ASF logo.jpg
 
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==Virulence and Pathogenesis==
 
==Virulence and Pathogenesis==
 
*Infects either '''upper respiratory tract''' or '''skin''' via '''ticks'''
 
*Infects either '''upper respiratory tract''' or '''skin''' via '''ticks'''
*Enters bloodstream in [[Monocytes - WikiBlood|monocytes]]
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*Enters bloodstream in [[Monocytes|monocytes]]
 
*Reaches viscera and bone marrow within days
 
*Reaches viscera and bone marrow within days
 
*Induces a '''clotting defect''' and '''hemolysis''' in red blood cells
 
*Induces a '''clotting defect''' and '''hemolysis''' in red blood cells
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**Antigen-stimulated B-cells undergo apoptosis rather than producing antibody
 
**Antigen-stimulated B-cells undergo apoptosis rather than producing antibody
 
*General cell signal transduction is blocked, decreasing non-specific immunity
 
*General cell signal transduction is blocked, decreasing non-specific immunity
[[Category:Viruses]]
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[[Category:Viral Organisms]]
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[[Category:To_Do_-_Clinical/Viruses]]
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