Changes

== Introduction ==

== Introduction ==

This is a rare syndrome is a complex of xerophthalmia and xerostomia due to lymphocyte-mediated destruction of exocrine glands of [[Salivary Glands - Anatomy & Physiology|salivary glands]]. Both those terms refer to cessation of production of tear or [[Salivary Glands - Anatomy & Physiology#Saliva|saliva]] production respectively. It may be caused by a primary autoimmune defect or part of another autoimmune condition.

This is a rare syndrome is a complex of xerophthalmia and xerostomia due to lymphocyte-mediated destruction of exocrine glands of [[Salivary Glands - Anatomy & Physiology|salivary glands]]. Both those terms refer to cessation of production of tear or [[Salivary Glands - Anatomy & Physiology#Saliva|saliva]] respectively. It may be caused by a primary autoimmune defect or part of another autoimmune condition.

Other causes of xerostomia include dysautonomia, infectious sialadenitis, neoplasia, salivary amyloidosis, head and neck radiation, drugs or autolytic disease.  

Other causes of xerostomia include dysautonomia, infectious sialadenitis, neoplasia, salivary amyloidosis, head and neck radiation, drugs or autolytic disease.  

== Clinical Signs ==

== Clinical Signs ==

Keratoconjunctivitis (dry eye), ulcers of the eye, difficulty swallowing, [[stomatitis]], [[gingivitis]] and [[glossitis]] are all possible clinical signs.

Keratoconjunctivitis (dry eye), ulcers of the eye, difficulty swallowing, [[stomatitis]], [[Periodontal Disease|gingivitis]] and [[glossitis]] are all possible clinical signs.

Guarded to Poor

Guarded to Poor

== References ==

== References ==

[[Category:Salivary_Glands_-_Pathology]] [[Category:Expert_Review]]

[[Category:Salivary_Glands_-_Pathology]] [[Category:Expert_Review]]