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*Xerophthalmia and xerostomia due to lymphocyte-mediated destruction of exocrine glands of [[Salivary Glands - Anatomy & Physiology|salivary glands]].
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*Both those terms refer to cessation of production of tear or [[Salivary Glands - Anatomy & Physiology#Saliva|saliva]] production respectively.
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== Introduction ==
*May be primary autoimmune or part of another autoimmune condition.
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*Causes of xerostomia:
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**Dysautonomia
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**Infectious sialadenitis
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**Neoplasia
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**Salivary amyloidosis
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**Head and neck radiation
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**Drugs
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**AutoI disease.
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'''Tagging-PG'''
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This is a rare syndrome is a complex of xerophthalmia and xerostomia due to lymphocyte-mediated destruction of exocrine glands of [[Salivary Glands - Anatomy & Physiology|salivary glands]]. Both those terms refer to cessation of production of tear or [[Salivary Glands - Anatomy & Physiology#Saliva|saliva]] respectively. It may be caused by a primary autoimmune defect or part of another autoimmune condition.
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[[Category:Salivary Glands - Pathology]]
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Other causes of xerostomia include dysautonomia, infectious sialadenitis, neoplasia, salivary amyloidosis, head and neck radiation, drugs or autolytic disease.
[[Category:To_Do_-_Clinical]]
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== Clinical Signs ==
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Keratoconjunctivitis (dry eye), ulcers of the eye, difficulty swallowing, [[stomatitis]], [[Periodontal Disease|gingivitis]] and [[glossitis]] are all possible clinical signs.
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== Diagnosis ==
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Diagnosis by elimination of all other causes of these clinical signs.
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== Treatment ==
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None
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Supportive treatments to treat clinical signs can be used such as eye lubrication, cleaning and cleansing the mouth and pain relief.
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== Prognosis ==
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Guarded to Poor
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{{Learning
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|Vetstream = [https://www.vetstream.com/canis/Content/Disease/dis60223.asp Sjogren's-like syndrome]
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}}
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== References ==
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Merck & Co (2008) The Merck Veterinary Manual (Eighth Edition) Merial
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Nelson, R.W. and Couto, C.G. (2009) Small Animal Internal Medicine (Fourth Edition) Mosby Elsevier.
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Tilley, L.P. and Smith, F.W.K.(2004)The 5-minute Veterinary Consult (Third edition) Lippincott, Williams & Wilkins.
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{{review}}
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{{OpenPages}}
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[[Category:Salivary_Glands_-_Pathology]] [[Category:Expert_Review]]
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