Line 1: |
Line 1: |
− | *Xerophthalmia and xerostomia due to lymphocyte-mediated destruction of exocrine glands of [[Salivary Glands - Anatomy & Physiology|salivary glands]].
| + | {{OpenPagesTop}} |
− | *Both those terms refer to cessation of production of tear or [[Salivary Glands - Anatomy & Physiology#Saliva|saliva]] production respectively.
| + | == Introduction == |
− | *May be primary autoimmune or part of another autoimmune condition.
| |
− | *Causes of xerostomia:
| |
− | **Dysautonomia
| |
− | **Infectious sialadenitis
| |
− | **Neoplasia
| |
− | **Salivary amyloidosis
| |
− | **Head and neck radiation
| |
− | **Drugs
| |
− | **AutoI disease.
| |
| | | |
− | '''Tagging-PG'''
| + | This is a rare syndrome is a complex of xerophthalmia and xerostomia due to lymphocyte-mediated destruction of exocrine glands of [[Salivary Glands - Anatomy & Physiology|salivary glands]]. Both those terms refer to cessation of production of tear or [[Salivary Glands - Anatomy & Physiology#Saliva|saliva]] respectively. It may be caused by a primary autoimmune defect or part of another autoimmune condition. |
| | | |
− | [[Category:Salivary Glands - Pathology]] | + | Other causes of xerostomia include dysautonomia, infectious sialadenitis, neoplasia, salivary amyloidosis, head and neck radiation, drugs or autolytic disease. |
− | [[Category:To_Do_-_Clinical]] | + | |
| + | |
| + | == Clinical Signs == |
| + | |
| + | Keratoconjunctivitis (dry eye), ulcers of the eye, difficulty swallowing, [[stomatitis]], [[Periodontal Disease|gingivitis]] and [[glossitis]] are all possible clinical signs. |
| + | |
| + | |
| + | == Diagnosis == |
| + | |
| + | Diagnosis by elimination of all other causes of these clinical signs. |
| + | |
| + | |
| + | == Treatment == |
| + | |
| + | None |
| + | |
| + | Supportive treatments to treat clinical signs can be used such as eye lubrication, cleaning and cleansing the mouth and pain relief. |
| + | |
| + | |
| + | == Prognosis == |
| + | |
| + | Guarded to Poor |
| + | |
| + | |
| + | {{Learning |
| + | |Vetstream = [https://www.vetstream.com/canis/Content/Disease/dis60223.asp Sjogren's-like syndrome] |
| + | }} |
| + | |
| + | == References == |
| + | |
| + | Merck & Co (2008) The Merck Veterinary Manual (Eighth Edition) Merial |
| + | |
| + | Nelson, R.W. and Couto, C.G. (2009) Small Animal Internal Medicine (Fourth Edition) Mosby Elsevier. |
| + | |
| + | Tilley, L.P. and Smith, F.W.K.(2004)The 5-minute Veterinary Consult (Third edition) Lippincott, Williams & Wilkins. |
| + | |
| + | |
| + | {{review}} |
| + | |
| + | {{OpenPages}} |
| + | |
| + | [[Category:Salivary_Glands_-_Pathology]] [[Category:Expert_Review]] |