Changes

==Overview==

==Overview==

  2007 '''Schematic structure of Insulin-like growth factor-1.''']]

  2007 '''Schematic structure of Insulin-like growth factor-1.''']]

IGF-1 is one of a number of Insulin-like growth factors. Insulin-Like Growth Factors are produced by many different tissues and have local paracrine and autocrine effects. (see [[Hormones - Anatomy & Physiology|hormones]] for further details). They bind to carrier proteins to extend their half life in the blood. The '''liver''' is the main source of IGF-1.

IGF-1 is one of a number of insulin-like growth factors. Insulin-like growth factors are produced by many different tissues and have local paracrine and autocrine effects. (see [[Hormones - Anatomy & Physiology|hormones]] for further details). They bind to carrier proteins to extend their half life in the blood. The [[Liver - Anatomy & Physiology|'''liver''']] is the main source of IGF-1. Hormones that directly stimulate Insulin-like growth factor-I (IGF-I) include growth hormone, insulin and oestradiol.Growth hormone is the main regulator of IGF-I production in the liver and insulin and oestradiol are stimulatory in other tissues.

 

==Actions of IGF-1==

==Actions of IGF-1==

Increased '''protein synthesis''' and increased '''chondrogenesis''', both promoting growth.

Increased '''protein synthesis''' and increased '''chondrogenesis''', both promoting growth.

[[Category:Endocrine System - Anatomy & Physiology]]

[[Category:Endocrine System - Anatomy & Physiology]]

[[Category:To Do - AimeeHicks]][[Category:To Do - Review]]

[[Category:A&P Done]]