Changes

==The Renal Corpuscle==

==The Renal Corpuscle==

* These capillaries do not connect to venules as with other capillaries

* These capillaries do not connect to venules as with other capillaries

* Blood flows into these capillaries through a wide afferent arteriole and leaves through a narrower efferent arteriole

* Blood flows into these capillaries through a wide afferent arteriole and leaves through a narrower efferent arteriole

* The flow from the efferant arteriole enters the [[The Formation of the Filtrate by the Glomerular Apparatus- Anatomy & Physiology#Pressure in the Peritubular Capillaries|peritubular capillaries]] surrounding the proximal tubule

* The flow from the efferant arteriole enters the [[Glomerular Apparatus and Filtration - Anatomy & Physiology#Pressure in the Peritubular Capillaries|peritubular capillaries]] surrounding the proximal tubule

* This change in diameter maintains a high filtration pressure which is essential for filtration

* This change in diameter maintains a high filtration pressure which is essential for filtration

* Also the blood entering the afferent arteriole is at very high pressure already as it from the renal artery

* Also the blood entering the afferent arteriole is at very high pressure already as it from the renal artery

* The pressure actually forces molecules through the [[The Formation of the Filtrate by the Glomerular Apparatus- Anatomy & Physiology#Glomerular Filtration|'''glomerular filtration barrier''']] which is responsible for selectively filtering the blood forming the glomerular filtrate.

* The pressure actually forces molecules through the [[Glomerular Apparatus and Filtration - Anatomy & Physiology#Glomerular Filtration|'''glomerular filtration barrier''']] which is responsible for selectively filtering the blood forming the glomerular filtrate.

* As well as the the cells in the blood vessels the other component of the glomerulus are the mesangial cells:

* As well as the the cells in the blood vessels the other component of the glomerulus are the mesangial cells:

** These give support to the glomerulus

** These give support to the glomerulus

* Surrounds the capillaries of the glomerulus

* Surrounds the capillaries of the glomerulus

* Has two layers

* Has two layers separated by the '''urinary space'''

** Inner visceral layer - Podocytes

** Inner visceral layer - Podocytes

** Outer parietal layer

** Outer parietal layer

===The Physiology of the Renal Corpuscle===

===The Physiology of the Renal Corpuscle===

Details of the physiology of the renal corpuscle can be found [[The Formation of the Filtrate by the Glomerular Apparatus- Anatomy & Physiology#Glomerular Filtration|here]]

Details of the physiology of the renal corpuscle can be found [[Glomerular Apparatus and Filtration - Anatomy & Physiology#Glomerular Filtration|here]]

==Proximal Tubule==

==Proximal Tubule==

Use the [[Microscopic Anatomy of the Nephron - Renal Flash Cards - Anatomy & Physiology|flash card revision resource]] for this section to test yourself.

Use the [[Microscopic Anatomy of the Nephron - Renal Flash Cards - Anatomy & Physiology|flash card revision resource]] for this section to test yourself.