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Skin Congenital and Hereditary - Pathology (view source)
Revision as of 11:58, 31 July 2008
, 11:58, 31 July 2008no edit summary
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===Acanthosis Nigricans===
===Acanthosis Nigricans===
*Occurs in Dachshunds
*Occurs in Dachshunds
*Bilateral axillary hyperpigmentation, [[Skin Glossary - Pathology|lichenification, alopecia]]
*Bilateral axillary hyperpigmentation, [[Skin Glossary - Pathology|lichenification, alopecia]]
**[[Skin Glossary - Pathology|Hyperkeratosis]]
**[[Skin Glossary - Pathology|Hyperkeratosis]]
**Increased melanin in epidermis
**Increased melanin in epidermis
===Alopecia and Hypotrichosis===
===Alopecia and Hypotrichosis===
*Occurs in most species
*Occurs in most species
*Bred for in some breeds, e.g. Mexican hairless dog, Sphinx cat
*Bred for in some breeds, e.g. Mexican hairless dog, Sphinx cat
*May be due to decreased number of hair follicles, failure of hair growth or follicular dysplasia
*May be due to decreased number of hair follicles, failure of hair growth or follicular dysplasia
*Also associated with maternal deficiency of iodine
*Also associated with maternal deficiency of iodine
===Collagen Dysplasia===
===Collagen Dysplasia===
[[Image: Collagen dysplasia.jpg|100px|thumb|right|<small><center>Collagen dysplasia - dog tail (Courtesy of Bristol BioMed Image Archive)</center></small>]]
[[Image: Collagen dysplasia.jpg|100px|thumb|right|<small><center>Collagen dysplasia - dog tail (Courtesy of Bristol BioMed Image Archive)</center></small>]]
*Occurs in many species
*Occurs in many species
*Very stretchy and loose skin that tears easily
*Very stretchy and loose skin that tears easily
**May appear normal
**May appear normal
**Collagen bundles varied in shape, size and their organisation
**Collagen bundles varied in shape, size and their organisation
===Epidermolysis Bullosa===
===Epidermolysis Bullosa===
[[Image: Epidermolysis bullosa.jpg|100px|thumb|right|<small><center>Epidermolysis bullosa in a lamb (Courtesy of Bristol BioMed Image Archive)</center></small>]]
[[Image: Epidermolysis bullosa.jpg|100px|thumb|right|<small><center>Epidermolysis bullosa in a lamb (Courtesy of Bristol BioMed Image Archive)</center></small>]]
*Also called '''Red Foot Disease'''
*Also called '''Red Foot Disease'''
**Healing displaces lesions more dorsally
**Healing displaces lesions more dorsally
**May become infected and form [[Skin Glossary - Pathology|pustules]]
**May become infected and form [[Skin Glossary - Pathology|pustules]]
===Epitheliogenesis Imperfecta===
===Epitheliogenesis Imperfecta===
*Also called '''Aplasia Cutis'''
*Also called '''Aplasia Cutis'''
*Incomplete development of squamous epithelium and [[Skin Glossary - Pathology|adnexa]] of skin and epithelium of oral mucosa
*Incomplete development of squamous epithelium and [[Skin Glossary - Pathology|adnexa]] of skin and epithelium of oral mucosa
**Circumscribed areas of missing squamous epithelium
**Circumscribed areas of missing squamous epithelium
*Unprotected underlying tissue gets easily damaged and infected, possibly resulting in bacteraemia
*Unprotected underlying tissue gets easily damaged and infected, possibly resulting in bacteraemia
===Hypertrichosis===
===Hypertrichosis===
*Increased hair growth
*Increased hair growth
*Both congenital or hereditary
*Both congenital or hereditary
**Enlarged primary follicles and wool fibres
**Enlarged primary follicles and wool fibres
*Also accociated with maternal hyperthermia
*Also accociated with maternal hyperthermia
===Ichthyosis===
===Ichthyosis===
*Inherited cutaneous disease
*Inherited cutaneous disease
*Occurs in dogs and cattle
*Occurs in dogs and cattle
**Ichthiosis fetalis - fatal, stillborn calves or die within days of birth
**Ichthiosis fetalis - fatal, stillborn calves or die within days of birth
**Ichthiosis congenita - folded and thickened skin, fissures and partial [[Skin Glossary - Pathology|alopecia]]
**Ichthiosis congenita - folded and thickened skin, fissures and partial [[Skin Glossary - Pathology|alopecia]]
===Photosensitisation===
===Photosensitisation===
*May be due to inherited defects
*May be due to inherited defects
*See [[Skin - environmental#Photosensitisation|HERE]]
*See [[Skin - environmental#Photosensitisation|HERE]]
===Porcine Juvenile Pustular Psoriasiform Dermatitis===
===Porcine Juvenile Pustular Psoriasiform Dermatitis===
*Also called '''Pityriasis Rosea'''
*Also called '''Pityriasis Rosea'''
*Occurs in pigs
*Occurs in pigs
**Epidermal hyperplasia, [[Skin Glossary - Pathology|parakeratosis]], epidermal [[Skin Glossary - Pathology|pustules]] and superficial perivascular dermatitis
**Epidermal hyperplasia, [[Skin Glossary - Pathology|parakeratosis]], epidermal [[Skin Glossary - Pathology|pustules]] and superficial perivascular dermatitis
*For more detail see [[Porcine Juvenile Pustular Psoriasiform Dermatitis]]
*For more detail see [[Porcine Juvenile Pustular Psoriasiform Dermatitis]]
===Zinc-related disorders===
===Zinc-related disorders===
*Occurs in Bullterriers and calves
*Occurs in Bullterriers and calves
*Resolves with zinc supplementation in calves but not dogs
*Resolves with zinc supplementation in calves but not dogs