Difference between revisions of "Total Water Balance - Physiology"
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| + | |linkpage =Water Balance and Homeostasis - Physiology | ||
| + | |linktext =WATER MAIN PAGE | ||
| + | |maplink = Urinary System (Content Map) - Anatomy & Physiology | ||
| + | |pagetype =Anatomy | ||
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==Introduction== | ==Introduction== | ||
It is best that the fluid surrounding the cells remains fairly constant. If volume is varied dramatically then it has major knock on effects on the blood pressure and perfusion of the organs and tissue. | It is best that the fluid surrounding the cells remains fairly constant. If volume is varied dramatically then it has major knock on effects on the blood pressure and perfusion of the organs and tissue. | ||
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==Inter-Animal Differences== | ==Inter-Animal Differences== | ||
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==Water Locations== | ==Water Locations== | ||
| − | Although 65% of water is found intracellulary there is a significant quantity in the digestive and urinary tracts. In ruminants this could equal the volume of the interstial fluid. This water is not easy to mobilise but can be if | + | Although 65% of water is found intracellulary there is a significant quantity in the digestive and urinary tracts. In ruminants this could equal the volume of the interstial fluid. This water is not easy to mobilise but can be if required to stabilise blood volume. |
==Water Gain and Loss== | ==Water Gain and Loss== | ||
| − | Water volume varies very little from day to day suggesting intake is equal to loss. Water is gained from three sources - drinking, food and metabolic water. In the periods between water intake ADH is secreted because the osmolarity of the plasma increases. Once the osmolarity reaches a certain threshold the thirst centre makes | + | Water volume varies very little from day to day suggesting intake is equal to loss. Water is gained from three sources - drinking, food and metabolic water. In the periods between water intake ADH is secreted because the osmolarity of the plasma increases. Once the osmolarity reaches a certain threshold the thirst centre makes to animal drink. However intake is not under precise control. Metabolic water is derived from the oxidation of hydrogen within cells and represents about 8-12% of an animals water supply. However this can be quite extreme. For example the kangaroo rat survives almost fully on this metabolic water. |
| − | If water gain and loss is to be balanced then the loss | + | If water gain and loss is to be balanced then the loss need to be adjusted to match the variable intake. Water is lost from, 4/5 main areas - the body surface, the airways, faeces, urine and lactation <sub>(if applicable)</sub>. |
===Insensible Water Loss=== | ===Insensible Water Loss=== | ||
| − | Insensible water loss is water loss which cannot be sensed by the individual and | + | '''Insensible water loss''' is water loss which cannot be sensed by the individual and tend to be a response to thermoregulation rather than being a regulated process of water homeostasis. It includes evaporation from the skin and epithelial surfaces of the airways and varies with environmental temperature and humidity as well as air movement. The main losses being from sweating and increased respiration. |
===Water Loss Through the Faeces=== | ===Water Loss Through the Faeces=== | ||
| − | This is minimal in omnivores and carnivores but of major | + | This is minimal in omnivores and carnivores but of major important to herbivorous species. It is not really under physiological control with regards to water balance and as such is not a viable means to adjusting the output to match to intake. |
===[[Aquaporins of the Kidney and Water Homeostasis - Anatomy & Physiology|Renal Regulation of Water Loss]]=== | ===[[Aquaporins of the Kidney and Water Homeostasis - Anatomy & Physiology|Renal Regulation of Water Loss]]=== | ||
| − | Only the | + | Only the kidenys are capable of precise adjustment of water loss to compensate for the variation in water intake. However a minimum amount must always be excreted to remove the waste. For example of '''70kg human''' produced '''600mosmol''' of solutes every 24 hours even without food. This is mainly Urea, Uric acid, phosphate, creatine, creatinine other waste products and ions. In humans the maximum urine osmolarity is '''1200mosmol/l''' therefore their is a minimum water loss of '''500ml''' even when no food or water is available. When this is added to another '''500ml in the exhaled air''' and '''400ml evaporated''' from the body surfaces a person loses 1400ml of water per 24 hours. This is the '''inevitable water loss.''' '''300ml of metabolic water''' is produced per 24 hours in this person leaving an '''1100ml''' deficit to be compensated for by drinking. |
===Water Intake and Lactation=== | ===Water Intake and Lactation=== | ||
| − | Water intake during lactation increases significantly even over and | + | Water intake during lactation increases significantly even over and aboce the requirement for milk. To produce 31l of milk and cow needs to take an extra 57l of water. This is thought to be because of an increased loss from the airways, skin and faeces. |
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Revision as of 16:28, 19 August 2008
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Introduction
It is best that the fluid surrounding the cells remains fairly constant. If volume is varied dramatically then it has major knock on effects on the blood pressure and perfusion of the organs and tissue.
Inter-Animal Differences
There are differences in water content between the many tissues which make up the body. Tissues which have low metabolic activity such as adipose tissue and bone have relatively lower water content. This leads to a variation in water between individuals for example a very fat cow may only have a 40% body water content compared to 70% in a lean cow. There is also an age difference. Young animals tend to have a high body water content where as older well nourished animal have a lower.
Due to the differences in relative tissue distribution there is a sex related difference also. Males which tend to have more muscle have a higher water content where as female which tend to have more adipose tissue have a lower.
Water Locations
Although 65% of water is found intracellulary there is a significant quantity in the digestive and urinary tracts. In ruminants this could equal the volume of the interstial fluid. This water is not easy to mobilise but can be if required to stabilise blood volume.
Water Gain and Loss
Water volume varies very little from day to day suggesting intake is equal to loss. Water is gained from three sources - drinking, food and metabolic water. In the periods between water intake ADH is secreted because the osmolarity of the plasma increases. Once the osmolarity reaches a certain threshold the thirst centre makes to animal drink. However intake is not under precise control. Metabolic water is derived from the oxidation of hydrogen within cells and represents about 8-12% of an animals water supply. However this can be quite extreme. For example the kangaroo rat survives almost fully on this metabolic water.
If water gain and loss is to be balanced then the loss need to be adjusted to match the variable intake. Water is lost from, 4/5 main areas - the body surface, the airways, faeces, urine and lactation (if applicable).
Insensible Water Loss
Insensible water loss is water loss which cannot be sensed by the individual and tend to be a response to thermoregulation rather than being a regulated process of water homeostasis. It includes evaporation from the skin and epithelial surfaces of the airways and varies with environmental temperature and humidity as well as air movement. The main losses being from sweating and increased respiration.
Water Loss Through the Faeces
This is minimal in omnivores and carnivores but of major important to herbivorous species. It is not really under physiological control with regards to water balance and as such is not a viable means to adjusting the output to match to intake.
Renal Regulation of Water Loss
Only the kidenys are capable of precise adjustment of water loss to compensate for the variation in water intake. However a minimum amount must always be excreted to remove the waste. For example of 70kg human produced 600mosmol of solutes every 24 hours even without food. This is mainly Urea, Uric acid, phosphate, creatine, creatinine other waste products and ions. In humans the maximum urine osmolarity is 1200mosmol/l therefore their is a minimum water loss of 500ml even when no food or water is available. When this is added to another 500ml in the exhaled air and 400ml evaporated from the body surfaces a person loses 1400ml of water per 24 hours. This is the inevitable water loss. 300ml of metabolic water is produced per 24 hours in this person leaving an 1100ml deficit to be compensated for by drinking.
Water Intake and Lactation
Water intake during lactation increases significantly even over and aboce the requirement for milk. To produce 31l of milk and cow needs to take an extra 57l of water. This is thought to be because of an increased loss from the airways, skin and faeces.