Difference between revisions of "Gut Development - Anatomy & Physiology"

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(New page: <big><center>'''BACK TO DEVELOPMENTAL BIOLOGY</center></big> ==Introduction== The endoderm will form the lining of the gut and the organ...)
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<big><center>[[Developmental Biology - Anatomy & Physiology|'''BACK TO DEVELOPMENTAL BIOLOGY]]</center></big>
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== Introduction  ==
 
  
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The endoderm will form the lining of the gut and the organs that develop from it. Splanchnic mesoderm surrounds the endoderm and orginates from the lateral plate mesoderm. It will form the smooth [[Muscles - Anatomy & Physiology|muscle]] of the gut that are used in peristalsis. <br> <br>
 
  
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== Endoderm Development  ==
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==Introduction==
  
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During endodermal development, the anterior end of the embryo invaginates. This invagination is called the '''anterior intestinal portal''' or '''(AIP)'''. The opposing anterior ends of the endoderm are brought together by this invagination, allowing both ends to fuse together to close the endoderm. A similar process occurs at the posterior of the embryo where an invagination occurs called the '''caudal intestinal portal''' or '''(CIP)'''. This invagination closes the posterior of the endoderm. The invagination and closure spread to the middle of the anterior - posterior axis where they meet at the yolk stalk. After the yolk has been metabolised, the yolk stalk can be closed. <br> <br>
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The endoderm will form the lining of the gut and the organs that develop from it. Splanchnic mesoderm surrounds the endoderm and orginates from the lateral plate mesoderm. It will form the smooth muscle of the gut that are used for peristalsis.
  
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== Regionalisation of the Gut  ==
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==Endoderm Development==
  
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The gut tube will develop into the [[Oesophagus - Anatomy & Physiology|oesophagus]], [[Monogastric Stomach - Anatomy & Physiology|stomach]], [[Small Intestine Overview - Anatomy & Physiology|small intestine]], [[Large Intestine - Anatomy & Physiology|large intestine]] and [[Anus - Anatomy & Physiology|anus]]. Regionalisation of these tissues occurs through co-ordinated endoderm and splanchnic mesoderm development. The endoderm governs splanchnic mesoderm development by releasing a signalling factor (sonic hedgehog) which induces differential mesoderm development. Sonic hedgehog controls '''HOX - A''' gene expression. The gut tube is closed at both ends during early development by the anterior '''buccopharyngeal membrane''' and the posterior '''cloacal membrane'''. As the head folds ventrally, it comes into contact with the buccopharyngeal membrane causing it to break down and opening the '''buccal cavity''' which is lined by ectoderm. At the posterior, the ectoderm invaginates to contact the cloacal membrane inducing the cloacal membrane to break down. Once this has occurred, this opens the '''anal passage'''.  
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#At the anterior of the embryo, the endoderm invaginates.
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#*This invagination is called the '''Anterior Intestinal Portal (AIP)'''.
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#The ends of the endoderm are brought together by this invagination, which fuse together to close the endoderm.
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#A similar process occurs at the posterior of the embryo, an invagination occurs called the '''Caudal Intestinal Portal (CIP).
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[[Category:Developmental_Biology]][[Category:A&P_Done|Category:A&amp;P_Done]]
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#*This closes the endoderm at the posterior of the embryo.
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#The invagination and closure spread to the middle of the anterior - posterior axis where they meet at the yolk stalk.
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#After the yolk has been metabolised, the yolk stalk can be closed.

Revision as of 15:44, 31 August 2008

BACK TO DEVELOPMENTAL BIOLOGY


Introduction

The endoderm will form the lining of the gut and the organs that develop from it. Splanchnic mesoderm surrounds the endoderm and orginates from the lateral plate mesoderm. It will form the smooth muscle of the gut that are used for peristalsis.

Endoderm Development

  1. At the anterior of the embryo, the endoderm invaginates.
    • This invagination is called the Anterior Intestinal Portal (AIP).
  2. The ends of the endoderm are brought together by this invagination, which fuse together to close the endoderm.
  3. A similar process occurs at the posterior of the embryo, an invagination occurs called the Caudal Intestinal Portal (CIP).
    • This closes the endoderm at the posterior of the embryo.
  4. The invagination and closure spread to the middle of the anterior - posterior axis where they meet at the yolk stalk.
  5. After the yolk has been metabolised, the yolk stalk can be closed.
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