Difference between revisions of "Adrenogenital Syndrome"
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| − | + | {{toplink | |
| − | + | |backcolour =EED2EE | |
| − | + | |linkpage =Reproductive System - Anatomy & Physiology | |
| − | + | |linktext =Reproductive System | |
| − | + | |maplink = Reproductive System (Content Map) - Anatomy & Physiology | |
| − | + | |pagetype =Anatomy | |
| − | + | |sublink1=Reproductive System - Anatomy & Physiology#Fertilisation.2C Implantation and Early Embryonic Development | |
| − | + | |subtext1=FERTILISATION , IMPLANTATION AND EARLY EMBRYONIC DEVELOPMENT | |
| − | + | |sublink2=Fertilisation, Implantation and Early Embryonic Development -Sexual Differentiation- Anatomy & Physiology | |
| − | + | |subtext2=SEXUAL DIFFERENTIATION | |
| + | }} | ||
| + | <br> | ||
== Aetiology == | == Aetiology == | ||
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* Foetal [[Endocrine_System_-_Adrenal_Glands_-_Anatomy_%26_Physiology|Adrenal Gland]] is hyperactive and secretes large quantities of Adrenal Androgens, due to a '''21 hydroxylase mutation'''. | * Foetal [[Endocrine_System_-_Adrenal_Glands_-_Anatomy_%26_Physiology|Adrenal Gland]] is hyperactive and secretes large quantities of Adrenal Androgens, due to a '''21 hydroxylase mutation'''. | ||
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== Consequence == | == Consequence == | ||
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* Mullarian Ducts persist due to the absence of testes, hence absence of Sertoli cell MIH secretion. This allows formation of '''female internal genitalia'''. | * Mullarian Ducts persist due to the absence of testes, hence absence of Sertoli cell MIH secretion. This allows formation of '''female internal genitalia'''. | ||
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== Morphology == | == Morphology == | ||
Revision as of 13:37, 3 September 2008
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Aetiology
- Genotype is XX as should be female
- Ovaries develop normally
- Foetal Adrenal Gland is hyperactive and secretes large quantities of Adrenal Androgens, due to a 21 hydroxylase mutation.
Consequence
- Wolffian Ducts persist due to the presence of Androgens, thus allowing development of male internal and external genitalia.
- Mullarian Ducts persist due to the absence of testes, hence absence of Sertoli cell MIH secretion. This allows formation of female internal genitalia.
Morphology
- Appears male with a micropenis and scrotum
- Both male and female internal genitalia