Difference between revisions of "Innate Immunity Flashcards"

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===Actions and Tools of the Innate Immune System===
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{{toplink
<FlashCard questions="14">
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|q1=True or False: The innate immune system responds quicker to infection than the adaptive immune system
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|linkpage =Innate Immune System - WikiBlood
|a1=True
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|linktext =INNATE IMMUNE SYSTEM
|l1=Innate Immune System - Introduction
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|sublink1 =Flash Cards - WikiBlood
|q2=Pathogen-associated molecular patterns (PAMPs) are expressed by which type of cells?
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|subtext1 =WIKIBLOOD FLASHCARDS
|a2=
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|pagetype =Blood
*Lipopolysaccharides or Gram Negative bacteria
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*Peptidoglycans of gram-positive bacteria
 
*Mannose sugars
 
*D-isoform amino acids
 
|l2=Recognition of Microorganisms
 
|q3=What recognises PAMPs?
 
|a3=Pattern recognition receptors (PRRs)
 
|l3=Recognition of Microorganisms
 
|q4=Where in the cell are Toll-Like Receptors (TLRs) located?
 
|a4=Cell membrane
 
|l4=Recognition of Microorganisms
 
|q5=Where in the cell are NOD2 receptors located?
 
|a5=Cell cytoplasm
 
|l5=Recognition of Microorganisms
 
|q6=Which catabolic enzymes digest microbes after phagocytosis?
 
|a6=
 
*Glycosidases
 
*Lipases
 
*Proteases
 
|l6=Phagocytosis
 
|q7=True or False: Lysosomes do not use energy when they kill microbes
 
|a7=
 
*False
 
*Lysosomes fuse with phagosomes, killing microbes in an energy-dependent way
 
|l7=Phagocytosis
 
|q8=Name two physical barriers of the innate immune system
 
|a8=
 
*Skin
 
*Mucous membranes
 
|l8=Innate Immunity Barriers
 
|q9=Name 3 biochemical barriers of the innate immune system
 
|a9=
 
*Lactic and fatty acids
 
*Enzymes
 
*Mucous
 
|l9=Innate Immunity Barriers
 
|q10=What is the function of commensal organisms?
 
|a10=
 
*Produce natural antibiotics
 
*Outcompete pathogens at epithelial and mucosal surfaces
 
|l10=Innate Immunity Barriers
 
|q11=Complete the sentence about commensal organisms:
 
<p>When commensals are disturbed, infection with ??? organisms is ???</p>
 
|a11=
 
*opportunistic
 
*increased
 
|l11=Innate Immunity Barriers
 
|q12=Name the three main humoral factors and their principal action
 
|a12=
 
*Lysozyme
 
**Digests bacterial cell walls
 
*Complement
 
**Promotes phagocytosis or lysis of invading organisms
 
*Interferons
 
**Make uninfected cells resistant to infection and enhances expression of MHC molecules
 
|l12=Humoral Factors of Innate Immune System
 
|q13=Which granulocytes are components of the innate immune response to infection?
 
|a13=
 
*Neutrophils
 
*Eosinophils
 
*Basophils/mast cells
 
|l13=Innate Immunity Cellular Responses
 
|q14=Which other cells are components of the innate immune response to infection?
 
|a14=Monocytes
 
*Tissue mast cells
 
*Macrophages
 
|l14=Innate Immunity Cellular Responses
 
</FlashCard>
 
===Innate Immunity to Viruses===
 
<FlashCard questions="4">
 
|q1=What is the main element of a viral attack which the innate immune system can recognise?
 
|a1=Double stranded RNA (dsRNA)
 
|l1=Innate Immunity to Viruses
 
|q2=Where are TLR3's located in the cell and what do they recognise?
 
|a2=
 
*Cell surface
 
*Double stranded RNA (dsRNA)
 
|l2=Innate Immunity to Viruses
 
|q3=What are the funtions of Type I Interferon production in response to a viral attack?
 
|a3=
 
*Increases mRNA degredation
 
*Inhibits protein synthesis
 
*Increases antigen presentation to antibody
 
|l3=Innate Immunity to Viruses
 
|q4=Which cells are produced as the final line of response to viral attack and which cells do they target?
 
|a4=
 
*Natural Killer cells (NK cells)
 
*Targets cells with decreased levels of MHC on their surface
 
|l4=Innate Immunity to Viruses
 
</FlashCard>
 
===Innate Immunity to Bacteria===
 
<FlashCard questions="2">
 
|q1=What effects does the release of inflammatory cytokines have on the infected area?
 
|a1=
 
*White blood cell influx
 
*Vasodilation
 
*Increase in vascular permeability
 
*Sustains a rise in core temperature
 
*Mediates the release of acute phase proteins from the liver
 
*Mediates bone marrow mobilisation
 
|l1=Innate Immunity to Bacteria
 
|q2=Which cell is the most important effector cell in the innate response to bacterial infection?
 
|a2=Neutrophils
 
|l2=Innate Immunity to Bacteria
 
</FlashCard>
 
  
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{{Jim Bee 2007}}
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{| border="3" cellpadding="8"
[[Category:Immunology Flashcards]]
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[[Category:Innate Immune System|Z]]
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||[[Primary Lymphoid Tissue - Anatomy & Physiology|<span title="Answer article">Link to Answer Article</span>]]
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Revision as of 11:25, 4 September 2008

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INNATE IMMUNE SYSTEM
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